Role of cytokines in experimental and human visceral leishmaniasis

M Samant, U Sahu, SC Pandey… - Frontiers in cellular and …, 2021 - frontiersin.org
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

Immunobiology of visceral leishmaniasis

R Kumar, S Nylén - Frontiers in immunology, 2012 - frontiersin.org
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania
donovani and Leishmania infantum (Leishmania chagasi in the Americas). These …

Mechanisms of immune evasion in leishmaniasis

G Gupta, S Oghumu, AR Satoskar - Advances in applied microbiology, 2013 - Elsevier
Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …

[HTML][HTML] Multifunctional, TNF-α and IFN-γ-Secreting CD4 and CD8 T Cells and CD8High T Cells Are Associated With the Cure of Human Visceral Leishmaniasis

LS Rodrigues, AS Barreto, LGS Bomfim… - Frontiers in …, 2021 - frontiersin.org
Visceral leishmaniasis (VL) is a chronic and often fatal disease caused by protozoans of the
genus Leishmania that affects millions of people worldwide. Patients with symptomatic VL …

Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis

L Soong, CA Henard, PC Melby - Seminars in immunopathology, 2012 - Springer
The outcomes of Leishmania infection are determined by host immune and nutrition status,
parasite species, and co-infection with other pathogens. While subclinical infection and self …

Reciprocity between regulatory T cells and Th17 cells: relevance to polarized immunity in leprosy

S Sadhu, BK Khaitan, B Joshi, U Sengupta… - PLoS neglected …, 2016 - journals.plos.org
T cell defect is a common feature in lepromatous or borderline lepromatous leprosy (LL/BL)
patients in contrast to tuberculoid or borderline tuberculoid type (TT/BT) patients …