Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Optical imaging has become an indispensable technology in the clinic. The molecular
design of cell-targeted and highly sensitive materials, the validation of specific disease …

Background Despite significant improvements in preoperative workup and surgical
planning, surgeons often rely on their eyes and hands during surgery. Although this can be …

Purpose The aim of this review is to give an overview of the current status of targeted optical
fluorescence imaging in the field of oncology, cardiovascular, infectious and inflammatory …

Background Surgery is the cornerstone of colorectal cancer (CRC) treatment, yet complete
removal of the tumour remains a challenge. The second near-infrared window (NIR-II, 1000 …

Background Colorectal cancer is the fourth most diagnosed malignancy worldwide and
surgery is one of the cornerstones of the treatment strategy. Near-infrared (NIR) …

Significance This third biennial intraoperative molecular imaging (IMI) conference shows
how optical contrast agents have been applied to develop clinically significant endpoints …

Importance Unintended tumor-positive resection margins occur frequently during minimally
invasive surgery for colorectal liver metastases and potentially negatively influence …

Colorectal cancer remains a major cause of cancer death and morbidity worldwide. Surgery
is a major treatment modality for primary and, increasingly, secondary curative therapy …

Significance: Surgery is often paramount in the management of many solid organ
malignancies because optimal resection is a major factor in disease-specific survival …