Roles of HLA-G in the maternal-fetal immune microenvironment

X Xu, Y Zhou, H Wei - Frontiers in immunology, 2020 - frontiersin.org
During pregnancy, the maternal uterus and fetus form a special microenvironment at the
maternal-fetal interface to support fetal development. Extravillous trophoblasts (EVTs) …

Anti-inflammatory cytokines in endometriosis

WJ Zhou, HL Yang, J Shao, J Mei, KK Chang… - Cellular and molecular …, 2019 - Springer
Although the pathogenesis of endometriosis is not fully understood, it is often considered to
be an inflammatory disease. An increasing number of studies suggest that differential …

The composition of the gut microbiota throughout life, with an emphasis on early life

JM Rodríguez, K Murphy, C Stanton… - Microbial ecology in …, 2015 - Taylor & Francis
The intestinal microbiota has become a relevant aspect of human health. Microbial
colonization runs in parallel with immune system maturation and plays a role in intestinal …

The biology of thymic stromal lymphopoietin (TSLP)

SF Ziegler, F Roan, BD Bell, TA Stoklasek… - Advances in …, 2013 - Elsevier
Originally shown to promote the growth and activation of B cells, thymic stromal
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic …

Gimme shelter: the immune system during pregnancy

A Munoz‐Suano, AB Hamilton… - Immunological reviews, 2011 - Wiley Online Library
Antigen‐presenting molecules vary between individuals of the same species, making it more
difficult for pathogens to evade immune recognition and spread through the whole …

Crosstalk between trophoblasts and decidual immune cells: the cornerstone of maternal-fetal immunotolerance

L Xu, Y Li, Y Sang, DJ Li, M Du - Frontiers in immunology, 2021 - frontiersin.org
The success of pregnancy relies on the fine adjustment of the maternal immune system to
tolerate the allogeneic fetus. Trophoblasts carrying paternal antigens are the only fetal …

Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression

MK Oyoshi, RP Larson, SF Ziegler, RS Geha - Journal of allergy and clinical …, 2010 - Elsevier
BACKGROUND: Atopic dermatitis is characterized by scratching and by TH2-dominated
immune response to cutaneously introduced antigens. Antigen application to skin …

TSLP expression: cellular sources, triggers, and regulatory mechanisms

T Takai - Allergology International, 2012 - jstage.jst.go.jp
Thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine initially identified in the culture
supernatant of a thymic stromal cell line. Highly expressed in the epidermis in skin lesions of …

Immune cells at the fetomaternal interface: how the microenvironment modulates immune cells to foster fetal development

A Schumacher, DJ Sharkey, SA Robertson… - The Journal of …, 2018 - journals.aai.org
Immune cells adapt their phenotypic and functional characteristics in response to the tissue
microenvironment within which they traffic and reside. The fetomaternal interface, consisting …

The gut microbiota and its role in the development of allergic disease: a wider perspective

CE West, MC Jenmalm… - Clinical & Experimental …, 2015 - Wiley Online Library
The gut microbiota are critical in the homoeostasis of multiple interconnected host metabolic
and immune networks. If early microbial colonization is delayed, the gut‐associated …