Challenges and future directions of SUDEP models
JX Gu, WH Shao, L Liu, YL Wang, Y Yang, ZY Zhang… - Lab Animal, 2024 - nature.com
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among
patients with epilepsy, causing a global public health burden. The underlying mechanisms …
patients with epilepsy, causing a global public health burden. The underlying mechanisms …
Myocardial iron overload in an experimental model of sudden unexpected death in epilepsy
Uncontrolled repetitive generalized tonic-clonic seizures (GTCS) are the main risk factor for
sudden unexpected death in epilepsy (SUDEP). GTCS can be observed in models such as …
sudden unexpected death in epilepsy (SUDEP). GTCS can be observed in models such as …
Deciphering key regulators involved in epilepsy‐induced cardiac damage through whole transcriptome and proteome analysis in a rat model
Objective Sudden unexpected death in epilepsy (SUDEP) is a major outcome of cardiac
dysfunction in patients with epilepsy. In continuation of our previous work, the present study …
dysfunction in patients with epilepsy. In continuation of our previous work, the present study …
Protective effect of Nardostachys jatamansi extract against lithium-pilocarpine-induced spontaneous recurrent seizures and associated cardiac irregularities in a rat …
Ethnopharmacological relevance Nardostachys jatamansi (D. Don) DC. is a perennial
herbaceous medicinal plant widely used for the ethnomedical treatment of various ailments …
herbaceous medicinal plant widely used for the ethnomedical treatment of various ailments …
Inhibition of mammalian target of rapamycin attenuates recurrent seizures associated cardiac damage in a zebrafish kindling model of chronic epilepsy
Abstract Sudden Unexpected Death in Epilepsy (SUDEP) is primarily linked with the cardiac
irregularities that occur due to recurrent seizures. Our previous studies found a role of mTOR …
irregularities that occur due to recurrent seizures. Our previous studies found a role of mTOR …
A nomogram to predict symptomatic epilepsy in patients with radiation-induced brain necrosis
X Huang, X Zhang, X Wang, X Rong, Y Li, H Li… - Neurology, 2020 - AAN Enterprises
Objective To develop and validate a nomogram to predict epilepsy in patients with radiation-
induced brain necrosis (RN). Methods The nomogram was based on a retrospective …
induced brain necrosis (RN). Methods The nomogram was based on a retrospective …
[HTML][HTML] The number and periodicity of seizures induce cardiac remodeling and changes in micro-RNA expression in rats submitted to electric amygdala kindling …
Generalized tonic-clonic seizures (GTCS) are the main risk factor for sudden unexpected
death in epilepsy (SUDEP). Also, among the several mechanisms underlying SUDEP there …
death in epilepsy (SUDEP). Also, among the several mechanisms underlying SUDEP there …
[HTML][HTML] Altered cardiac structure and function is related to seizure frequency in a rat model of chronic acquired temporal lobe epilepsy
KL Powell, Z Liu, CL Curl, AJA Raaijmakers… - Neurobiology of …, 2021 - Elsevier
Objective This study aimed to prospectively examine cardiac structure and function in the
kainic acid-induced post-status epilepticus (post-KA SE) model of chronic acquired temporal …
kainic acid-induced post-status epilepticus (post-KA SE) model of chronic acquired temporal …
STAT3 but not STAT5 contributes to the protective effect of electroacupuncture against myocardial ischemia/reperfusion injury in mice
HH Guo, XY **g, H Chen, HX Xu, BM Zhu - Frontiers in Medicine, 2021 - frontiersin.org
Electroacupuncture (EA) can help reduce infarct size and injury resulting from myocardial
ischemia/reperfusion (I/R); however, the underlying molecular mechanism remains …
ischemia/reperfusion (I/R); however, the underlying molecular mechanism remains …
Targeting the PI3K/AKT/mTOR signaling pathway in primary central nervous system lymphoma: current status and future prospects
X Zhang, Y Liu - CNS & Neurological Disorders-Drug Targets …, 2020 - ingentaconnect.com
Primary Central Nervous System Lymphoma (PCNSL) is a rare invasive extranodal non-
Hodgkin lymphoma, a vast majority of which is Diffuse Large B-Cell Lymphoma (DLBCL) …
Hodgkin lymphoma, a vast majority of which is Diffuse Large B-Cell Lymphoma (DLBCL) …