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Efficacy and safety of JAK inhibitors in rheumatoid arthritis: update for the practising clinician
Janus kinase (JAK) inhibitors, including tofacitinib, baricitinib, upadacitinib and filgotinib, are
increasingly used in the treatment of rheumatoid arthritis (RA). There has been debate about …
increasingly used in the treatment of rheumatoid arthritis (RA). There has been debate about …
Selectivity, efficacy and safety of JAKinibs: new evidence for a still evolving story
Fundamental insight gained over the last decades led to the discovery of cytokines as
pivotal drivers of inflammatory diseases such as rheumatoid arthritis, psoriasis/psoriasis …
pivotal drivers of inflammatory diseases such as rheumatoid arthritis, psoriasis/psoriasis …
Pioneering a paradigm shift in asthma management: remission as a treatment goal
Until 2023, guidelines focused on asthma control as the primary goal of asthma treatment, 1
with the step-wise addition of drugs until the best possible disease control was achieved …
with the step-wise addition of drugs until the best possible disease control was achieved …
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update
JS Smolen, RBM Landewé, SA Bergstra… - Annals of the …, 2023 - ard.bmj.com
Objectives To provide an update of the EULAR rheumatoid arthritis (RA) management
recommendations addressing the most recent developments in the field. Methods An …
recommendations addressing the most recent developments in the field. Methods An …
Safety of biological and targeted synthetic disease-modifying antirheumatic drugs for rheumatoid arthritis as used in clinical practice: results from the ARTIS …
Objective Longitudinal clinical registry-infrastructures such as Anti-Rheumatic Therapies in
Sweden (ARTIS) allow simultaneous comparison of the safety of individual …
Sweden (ARTIS) allow simultaneous comparison of the safety of individual …
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases
Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …
[HTML][HTML] The role of marine n-3 polyunsaturated fatty acids in inflammatory-based disease: the case of rheumatoid arthritis
Inflammation is a conserved process that involves the activation of immune and non-immune
cells aimed at protecting the host from bacteria, viruses, toxins and injury. However …
cells aimed at protecting the host from bacteria, viruses, toxins and injury. However …
Therapeutic Potential of Plant-Derived Compounds and Plant Extracts in Rheumatoid Arthritis—Comprehensive Review
Rheumatoid arthritis (RA) is a persistent autoimmune disorder that is characterized by joint
inflammation, discomfort, and impairment. Despite the existence of several therapeutic …
inflammation, discomfort, and impairment. Despite the existence of several therapeutic …
Time and dose-dependent effect of systemic glucocorticoids on major adverse cardiovascular event in patients with rheumatoid arthritis: a population-based study
Objectives Cardiovascular event (CVE) risk in rheumatoid arthritis (RA) was increased by
glucocorticoids (GC) use. Whether there is a threshold dose and duration of GC use beyond …
glucocorticoids (GC) use. Whether there is a threshold dose and duration of GC use beyond …
Fibroblast-like synoviocytes-derived exosomal circFTO deteriorates rheumatoid arthritis by enhancing N6-methyladenosine modification of SOX9 in chondrocytes
G Li, Y Fang, N Xu, Y Ding, D Liu - Arthritis Research & Therapy, 2024 - Springer
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes
disability worldwide. Exosomes released by fibroblast-like synoviocytes in RA (RA-FLSs …
disability worldwide. Exosomes released by fibroblast-like synoviocytes in RA (RA-FLSs …