Transcription factor-based biosensors enlightened by the analyte

R Fernandez-López, R Ruiz, F de la Cruz… - Frontiers in …, 2015 - frontiersin.org
Whole cell biosensors (WCBs) have multiple applications for environmental monitoring,
detecting a wide range of pollutants. WCBs depend critically on the sensitivity and specificity …

Tailored bacteria tackling with environmental mercury: Inspired by natural mercuric detoxification operons

C Hui, B Ma, S Hu, C Wu - Environmental Pollution, 2024 - Elsevier
Mercury (Hg) and its inorganic and organic compounds significantly threaten the ecosystem
and human health. However, the natural and anthropogenic Hg environmental inputs …

AlphaFold2 models indicate that protein sequence determines both structure and dynamics

HB Guo, A Perminov, S Bekele, G Kedziora… - Scientific reports, 2022 - nature.com
Abstract AlphaFold 2 (AF2) has placed Molecular Biology in a new era where we can
visualize, analyze and interpret the structures and functions of all proteins solely from their …

The mercury resistance operon: from an origin in a geothermal environment to an efficient detoxification machine

ES Boyd, T Barkay - Frontiers in microbiology, 2012 - frontiersin.org
Mercuric mercury (Hg [II]) is a highly toxic and mobile element that is likely to have had a
pronounced and adverse effect on biology since Earth's oxygenation∼ 2.4 billion years ago …

Bioremediation: an effective approach of mercury removal from the aqueous solutions

L Rani, AL Srivastav, J Kaushal - Chemosphere, 2021 - Elsevier
Abstract Mercury (Hg (II)) is the 16th rarest element present in the earth's crust. Due to rapid
industrialization and urban expansions, the mercury concentration has been elevated in the …

Exploring the role of microbial proteins in controlling environmental pollutants based on molecular simulation

J Wu, J Lv, L Zhao, R Zhao, T Gao, Q Xu, D Liu… - Science of the Total …, 2023 - Elsevier
Molecular simulation has been widely used to study microbial proteins' structural
composition and dynamic properties, such as volatility, flexibility, and stability at the …

Microbial transformations in the mercury cycle

CC Lin, N Yee, T Barkay - Environmental chemistry and …, 2012 - Wiley Online Library
Microbial chemical transformations play a key role in geochemical cycles of most elements
by changing their redox states and by converting between organic and inorganic forms. As a …

[HTML][HTML] Microbial diversity of mer operon genes and their potential rules in mercury bioremediation and resistance

MM Naguib, AO El-Gendy… - The Open …, 2018 - openbiotechnologyjournal.com
Background: Mercury is a toxic metal that is present in small amounts in the environment, but
its level is rising steadily, due to different human activities, such as industrialization. It can …

Structural basis of the mercury (II)-mediated conformational switching of the dual-function transcriptional regulator MerR

CC Chang, LY Lin, XW Zou, CC Huang… - Nucleic acids …, 2015 - academic.oup.com
The mer operon confers bacterial resistance to inorganic mercury (Hg2+) and
organomercurials by encoding proteins involved in sensing, transport and detoxification of …

Isolation and characterization of mercury-resistant bacteria from wastewater sources in Egypt

MM Naguib, AS Khairalla, AO El-Gendy… - Canadian Journal of …, 2019 - cdnsciencepub.com
An important mechanism for microbial resistance to mercury is its reduction into elemental
mercury (facilitated by the merA gene). Thirty-eight microbial isolates from a variety of …