Mechanisms of memory under stress

L Schwabe, EJ Hermans, M Joëls, B Roozendaal - Neuron, 2022 - cell.com
It is well established that stress has a major impact on memory, driven by the concerted
action of various stress mediators on the brain. Recent years, however, have seen …

Stress, glucocorticoids and memory: implications for treating fear-related disorders

D de Quervain, L Schwabe… - Nature Reviews …, 2017 - nature.com
Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing
of emotionally arousing experiences. They enhance the consolidation of new memories …

A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo

A Dong, K He, B Dudok, JS Farrell, W Guan… - Nature …, 2022 - nature.com
Endocannabinoids (eCBs) are retrograde neuromodulators with important functions in a
wide range of physiological processes, but their in vivo dynamics remain largely …

The endocannabinoid system in guarding against fear, anxiety and stress

B Lutz, G Marsicano, R Maldonado… - Nature Reviews …, 2015 - nature.com
The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …

Amygdala microcircuits controlling learned fear

S Duvarci, D Pare - Neuron, 2014 - cell.com
We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction

O Gunduz-Cinar, LI Castillo, M **a, E Van Leer… - Neuron, 2023 - cell.com
Preclinical and clinical studies implicate endocannabinoids (eCBs) in fear extinction, but the
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …

[HTML][HTML] Amygdala inhibitory circuits regulate associative fear conditioning

S Krabbe, J Gründemann, A Lüthi - Biological psychiatry, 2018 - Elsevier
Associative memory formation is essential for an animal's survival by ensuring adaptive
behavioral responses in an ever-changing environment. This is particularly important under …

Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission

M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …