Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …

Cardiovascular disease is a leading cause of death, and translational research is needed to
understand better mechanisms whereby the left ventricle responds to injury. Mouse models …

Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer
the possibility to non-invasively probe whole-brain network dynamics and to investigate the …

Magnetic resonance spectroscopy (MRS) holds promise for understanding neurochemical
mechanisms associated with human cognitive aging in vivo. Recent advances in magnetic …

Peptide-based drug development for CNS disorders is challenged by poor blood-brain
barrier (BBB) penetrability of peptides. While acylation protractions (lipidation) have been …

The mammalian brain is composed of densely connected and interacting regions, which
form structural and functional networks. An improved understanding of the structure–function …

Multi-modal imaging is essential for advancing our understanding of brain function and
unraveling pathophysiological processes underlying neurological and psychiatric disorders …

The biological basis of the increased risk for psychiatric disorders seen in 15q11. 2 copy
number deletion is unknown. Previous work has shown disturbances in white matter tracts in …

With the central ability to visualize a variety of endogenous chromophores and biomarkers
or exogenous contrast agents, optoacoustic (photoacoustic) imaging empowers new …

Pupillometry, a noninvasive measure of arousal, complements human functional MRI (fMRI)
to detect periods of variable cognitive processing and identify networks that relate to …