Optimizing CAR-T cell therapy for solid tumors: current challenges and potential strategies
K Ai, B Liu, X Chen, C Huang, li** Yang… - Journal of Hematology & …, 2024 - Springer
Chimeric antigen receptor (CAR)-T cell therapy demonstrates substantial efficacy in various
hematological malignancies. However, its application in solid tumors is still limited. Clinical …
hematological malignancies. However, its application in solid tumors is still limited. Clinical …
Advancing genome editing with artificial intelligence: opportunities, challenges, and future directions
Clustered regularly interspaced short palindromic repeat (CRISPR)-based genome editing
(GED) technologies have unlocked exciting possibilities for understanding genes and …
(GED) technologies have unlocked exciting possibilities for understanding genes and …
[HTML][HTML] Artificial intelligence in cancer care: From diagnosis to prevention and beyond
M Farrokhi, A Moeini, F Taheri, M Farrokhi, M Mostafavi… - Kindle, 2023 - preferpub.org
Artificial Intelligence (AI) has made significant strides in revolutionizing cancer care,
encompassing various aspects from diagnosis to prevention and beyond. With its ability to …
encompassing various aspects from diagnosis to prevention and beyond. With its ability to …
[HTML][HTML] AI and Deep Learning in Understanding the Etiology and Pathogenesis of Cancers
Artificial intelligence (AI) and deep learning have emerged as powerful tools in
understanding the etiology and pathogenesis of cancers. These technologies help uncover …
understanding the etiology and pathogenesis of cancers. These technologies help uncover …
Personalized medicine in pancreatic cancer: the promise of biomarkers and molecular targeting with dr. Michael J. Pishvaian
V Cortiana, RH Abbas, H Chorya, J Gambill… - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic cancer, with its increasing incidence, is predicted to become
the second deadliest solid tumor by 2040, urging for improved diagnostic and treatment …
the second deadliest solid tumor by 2040, urging for improved diagnostic and treatment …
The transformative potential of AI-driven CRISPR-Cas9 genome editing to enhance CAR T-cell therapy
A Boretti - Computers in Biology and Medicine, 2024 - Elsevier
This narrative review examines the promising potential of integrating artificial intelligence
(AI) with CRISPR-Cas9 genome editing to advance CAR T-cell therapy. AI algorithms offer …
(AI) with CRISPR-Cas9 genome editing to advance CAR T-cell therapy. AI algorithms offer …
Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
M Puccetti, A Schoubben, S Giovagnoli… - International Journal of …, 2023 - mdpi.com
As an appealing alternative to treat and prevent diseases ranging from cancer to COVID-19,
mRNA has demonstrated significant clinical effects. Nanotechnology facilitates the …
mRNA has demonstrated significant clinical effects. Nanotechnology facilitates the …
Preclinical Anticipation of On-and Off-Target Resistance Mechanisms to Anti-Cancer Drugs: A Systematic Review
PJ Dziubańska-Kusibab, E Nevedomskaya… - International Journal of …, 2024 - mdpi.com
The advent of targeted therapies has led to tremendous improvements in treatment options
and their outcomes in the field of oncology. Yet, many cancers outsmart precision drugs by …
and their outcomes in the field of oncology. Yet, many cancers outsmart precision drugs by …
CRISPR/Cas and artificial intelligence to improve precision medicine: Future perspectives and potential limitations
M Khoshandam, H Soltaninejad, S Hosseinkhani… - Human Gene, 2024 - Elsevier
The CRISPR/Cas9 genome editing system is a unique and new technology that allows
genetics and medical researchers to modify or edit parts of the genome. This is achieved by …
genetics and medical researchers to modify or edit parts of the genome. This is achieved by …
Precision oncology revolution: CRISPR-Cas9 and PROTAC technologies unleashed
Cancer continues to present a substantial global health challenge, with its incidence and
mortality rates persistently reflecting its significant impact. The emergence of precision …
mortality rates persistently reflecting its significant impact. The emergence of precision …