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[HTML][HTML] Exosomes: potential disease biomarkers and new therapeutic targets
Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …
activation, and are present in different types of biological fluid. Exosomes are involved in the …
Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in …
Fear is an emotion that serves as a driving factor in how organisms move through the world.
In this review, we discuss the current understandings of the subjective experience of fear …
In this review, we discuss the current understandings of the subjective experience of fear …
A microRNA signature that correlates with cognition and is a target against cognitive decline
While some individuals age without pathological memory impairments, others develop age‐
associated cognitive diseases. Since changes in cognitive function develop slowly over time …
associated cognitive diseases. Since changes in cognitive function develop slowly over time …
A combined miRNA–piRNA signature to detect Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing huge
emotional and economic burden to our societies. An effective therapy has not been …
emotional and economic burden to our societies. An effective therapy has not been …
[HTML][HTML] An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene
A growing number of epigenome-wide association studies have demonstrated a role for
DNA methylation in the brain in Alzheimer's disease. With the aim of exploring peripheral …
DNA methylation in the brain in Alzheimer's disease. With the aim of exploring peripheral …
[HTML][HTML] Cognitive epigenetic priming: leveraging histone acetylation for memory amelioration
Highlights•Learning naturally enhances histone acetylation in the hippocampus.•Cognitive
impairments hinder increased acetylation during learning.•HDACi enhances acetylation and …
impairments hinder increased acetylation during learning.•HDACi enhances acetylation and …
Mouse models of neurodegeneration: Know your question, know your mouse
Many mutant mouse strains have been developed as models to investigate
neurodegenerative disease in humans. However, variability in results among studies using …
neurodegenerative disease in humans. However, variability in results among studies using …
[HTML][HTML] Formins in human disease
L Labat-de-Hoz, MA Alonso - Cells, 2021 - mdpi.com
Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …
being responsible for a human inherited disorder: a form of sensorineural hearing loss …
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Cell biologists generally consider that microtubules and actin play complementary roles in
long-and short-distance transport in animal cells. On the contrary, using melanosomes of …
long-and short-distance transport in animal cells. On the contrary, using melanosomes of …
Psychological Stress–Induced Immune Response and Risk of Alzheimer's Disease in Veterans from Operation Enduring Freedom and Operation Iraqi Freedom
Purpose Psychological stress is a significant health problem in veterans and their family
members. Traumatic brain injury (TBI) and stress lead to the onset, progression, and …
members. Traumatic brain injury (TBI) and stress lead to the onset, progression, and …