The surfaces of human internal organs are lined by a mucus layer that ensures symbiotic
relationships with commensal microbiome while protecting against potentially injurious …

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier
function, it has limitations such as overestimated transepithelial electrical resistance (TEER) …

Defective barrier function is a predisposing factor in inflammatory bowel disease (IBD) and
colitis-associated cancer (CAC). Although TGFβ signaling defects have been associated …

Aims: NADPH oxidase (NOX)-derived reactive oxygen species (ROS) are implicated in the
pathophysiology of hypertension in chronic kidney disease patients. Genetic deletion of …

Organoid culture provides a powerful technology that can bridge the gap between
monolayer cell culture on the one hand and whole animal or human subject research on the …

Abstract Light-emitting diodes (LED)-derived lights have been widely used as a medical
treatment in photobiomodulation (PBM). However, the PBM effects in ophthalmology are …

Background Recent studies demonstrated that Aquamin®, a calcium-, magnesium-rich, multi-
mineral natural product, improves barrier structure and function in colonoids obtained from …

The overall goal of this study was to determine whether Aquamin®, a calcium-, magnesium-,
trace element-rich, red algae-derived natural product, would alter the expression of proteins …

Introduction: Ulcerative colitis is a chronic inflammatory condition, and continuous
inflammatory stimulus may lead to barrier dysfunction. The goal of this study was to assess …

Enterococcus faecium is an opportunistic pathogen able to colonize the intestines of
hospitalized patients. This initial colonization is an important step in the downstream …