The making of a proprioceptor: a tale of two identities

JC de Nooij, N Zampieri - Trends in Neurosciences, 2023 - cell.com
Proprioception, the sense of body position in space, has a critical role in the control of
posture and movement. Aside from skin and joint receptors, the main sources of …

[HTML][HTML] Exploration biases forelimb reaching strategies

AC Mosberger, LJ Sibener, TX Chen, HFM Rodrigues… - Cell reports, 2024 - cell.com
The brain can generate actions, such as reaching to a target, using different movement
strategies. We investigate how such strategies are learned in a task where perched head …

An output-null signature of inertial load in motor cortex

EA Kirk, KT Hope, SJ Sober, BA Sauerbrei - Nature Communications, 2024 - nature.com
Coordinated movement requires the nervous system to continuously compensate for
changes in mechanical load across different conditions. For voluntary movements like …

Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex

T DeWolf, S Schneider, P Soubiran, A Roggenbach… - bioRxiv, 2024 - biorxiv.org
The neural activity of the brain is intimately coupled to the dynamics of the body. Yet how our
hierarchical sensorimotor system dynamically orchestrates the generation of movement …

Beyond barrels: diverse thalamocortical projection motifs in the mouse ventral posterior complex

M Rubio-Teves, P Martín-Correa… - Journal of …, 2024 - jneurosci.org
Thalamocortical pathways from the rodent ventral posterior (VP) thalamic complex to the
somatosensory cerebral cortex areas are a key model in modern neuroscience. However …

Decoding multi-limb movements from two-photon calcium imaging of neuronal activity using deep learning

S Park, M Lipton, MC Dadarlat - Journal of neural engineering, 2024 - iopscience.iop.org
Objective. Brain–machine interfaces (BMIs) aim to restore sensorimotor function to
individuals suffering from neural injury and disease. A critical step in implementing a BMI is …

Decoding multi-limb movements from low temporal resolution calcium imaging using deep learning

S Park, M Lipton, MC Dadarlat - bioRxiv, 2023 - biorxiv.org
Two-photon imaging has been a critical tool for dissecting brain circuits and understanding
brain function. However, relating slow two-photon calcium imaging data to fast behaviors …

Exploration biases how forelimb reaches to a spatial target are learned

AC Mosberger, LJ Sibener, TX Chen, HFM Rodrigues… - bioRxiv, 2023 - biorxiv.org
The brain can learn to generate actions, such as reaching to a target, using different
movement strategies. Understanding how different variables bias which strategies are …

Population-level encoding of somatosensation in mouse sensorimotor cortex

S Park, MH Lipton, M Dadarlat - bioRxiv, 2025 - biorxiv.org
Dexterous limb movements rely on somatosensation (touch and proprioception), which
provides the sense of the body's posture, movement, and interaction with objects. The …

Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse's hand

D Piña Novo, M Gao, J Yu, JM Barrett, GMG Shepherd - bioRxiv, 2024 - biorxiv.org
Spiking activity along synaptic circuits linking primary somatosensory (S1) and motor (M1)
areas is fundamental for sensorimotor integration in cortex. Circuits along the ascending …