Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and esca** the host immune response against it. HIV …

Nanoparticle-based drug delivery to the vagina: a review

LM Ensign, R Cone, J Hanes - Journal of Controlled Release, 2014 - Elsevier
Vaginal drug administration can improve prophylaxis and treatment of many conditions
affecting the female reproductive tract, including sexually transmitted diseases, fungal and …

[KIRJA][B] Fields' virology

BN Fields - 2007 - books.google.com
Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability

T Coetzee, N Fujita, J Dupree, R Shi, A Blight, K Suzuki… - Cell, 1996 - cell.com
The vertebrate nervous system is characterized by ensheathment of axons with myelin, a
multilamellar membrane greatly enriched in the galactolipid galactocerebroside (GalC) and …

Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication

ME Quiñones-Mateu, MM Lederman, Z Feng… - Aids, 2003 - journals.lww.com
Objective: Mechanisms underlying mucosal transmission of HIV-1 are incompletely
understood. We describe the anti-HIV-1 activity of human β-defensins (hBD), small cationic …

Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier

M Bomsel - Nature medicine, 1997 - nature.com
Contact between various epithelial cell lines and HIV chronically infected mononuclear cell
lines results in a massive and rapid budding of HIV virions toward the epithelium followed by …

HIV pathogenesis: 25 years of progress and persistent challenges

JA Levy - Aids, 2009 - journals.lww.com
In 1981, a new disease syndrome appeared in human populations in the United States and
elsewhere characterized by a deficiency in the immune system [1]. Patients presented with …

Lipid rafts and HIV-1: from viral entry to assembly of progeny virions

SM Campbell, SM Crowe, J Mak - Journal of Clinical Virology, 2001 - Elsevier
Background: Lipid rafts are currently an intensely investigated topic of cell biology. In
addition to a demonstrated role in signal transduction of the host cell, lipid rafts serve as …

A novel carbohydrate-glycosphingolipid interaction between a β-(1–3)-glucan immunomodulator, PGG-glucan, and lactosylceramide of human leukocytes

JW Zimmerman, J Lindermuth, PA Fish… - Journal of Biological …, 1998 - ASBMB
The immunomodulator Betafectin® PGG-glucan is a homopolymer of glucose derived from
yeast cell walls which has been demonstrated to enhance leukocyte anti-infective activity in …

The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection

S Bour, R Geleziunas, MA Wainberg - Microbiological reviews, 1995 - Am Soc Microbiol
Interactions between the viral envelope glycoprotein gp120 and the cell surface receptor
CD4 are responsible for the entry of human immunodeficiency virus type 1 (HIV-1) into host …