Abstract PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-
degradation strategy that has emerged in recent years. It uses bifunctional small molecules …

Aurora kinase B (AURKB) is a mitotic serine/threonine protein kinase that belongs to the
aurora kinase family along with aurora kinase A (AURKA) and aurora kinase C (AURKC) …

The Aurora kinases (A, B, and C) are a family of three isoform serine/threonine kinases that
regulate mitosis and meiosis. The Chromosomal Passenger Complex (CPC), which contains …

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As the second most common malignant tumor in the urinary system, renal cell carcinoma
(RCC) is imperative to explore its early diagnostic markers and therapeutic targets …

Abstract aurora B kinase is highly expressed in several cancer cells and promotes
tumorigenesis and progression, and therefore, it is an important target for drug to treat …

Aurora B is a serine/threonine kinase that has been implicated in regulating cell proliferation
in distinct cancers, including breast cancer. Here we show that Aurora B expression is …

Microtubules are the backbone of all eukaryotic cells cytoskeleton. Their dynamic behaviour
constitutes the basis for many biological processes such as cellular motility, cytoplasmic …

Background Ensuring genetic integrity is essential during the cell cycle to avoid aneuploidy,
one of the underlying causes of malignancies. Aurora kinases are serine/threonine kinase …

Kinesin family member 20A (KIF20A), an ideal cancer-testis antigen, was reported to be a
promising immunotherapeutic target for pancreatic cancers. Clinical trials of KIF20A peptide …