The applied principles of EEG analysis methods in neuroscience and clinical neurology

H Zhang, QQ Zhou, H Chen, XQ Hu, WG Li, Y Bai… - Military Medical …, 2023 - Springer
Electroencephalography (EEG) is a non-invasive measurement method for brain activity.
Due to its safety, high resolution, and hypersensitivity to dynamic changes in brain neural …

[HTML][HTML] Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the slee**
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance

LF Jiang-**e, A Drieu, K Bhasiin, D Quintero, I Smirnov… - Nature, 2024 - nature.com
The accumulation of metabolic waste is a leading cause of numerous neurological
disorders, yet we still have only limited knowledge of how the brain performs self-cleansing …

At-home wireless sleep monitoring patches for the clinical assessment of sleep quality and sleep apnea

S Kwon, HS Kim, K Kwon, H Kim, YS Kim, SH Lee… - Science …, 2023 - science.org
Although many people suffer from sleep disorders, most are undiagnosed, leading to
impairments in health. The existing polysomnography method is not easily accessible; it's …

An electrophysiological marker of arousal level in humans

JD Lendner, RF Helfrich, BA Mander, L Romundstad… - elife, 2020 - elifesciences.org
Deep non-rapid eye movement sleep (NREM) and general anesthesia with propofol are
prominent states of reduced arousal linked to the occurrence of synchronized oscillations in …

[HTML][HTML] Old brains come uncoupled in sleep: slow wave-spindle synchrony, brain atrophy, and forgetting

RF Helfrich, BA Mander, WJ Jagust, RT Knight… - Neuron, 2018 - cell.com
The coupled interaction between slow-wave oscillations and sleep spindles during non-
rapid-eye-movement (NREM) sleep has been proposed to support memory consolidation …

The neural circuits underlying general anesthesia and sleep

OA Moody, ER Zhang, KF Vincent, R Kato… - Anesthesia & …, 2021 - journals.lww.com
General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and
immobility. Important molecular targets of general anesthetics have been identified, but the …

Bidirectional prefrontal-hippocampal dynamics organize information transfer during sleep in humans

RF Helfrich, JD Lendner, BA Mander, H Guillen… - Nature …, 2019 - nature.com
How are memories transferred from short-term to long-term storage? Systems-level memory
consolidation is thought to be dependent on the coordinated interplay of cortical slow waves …

[HTML][HTML] Real-time dialogue between experimenters and dreamers during REM sleep

KR Konkoly, K Appel, E Chabani, A Mangiaruga, J Gott… - Current Biology, 2021 - cell.com
Dreams take us to a different reality, a hallucinatory world that feels as real as any waking
experience. These often-bizarre episodes are emblematic of human sleep but have yet to be …

Human REM sleep recalibrates neural activity in support of memory formation

JD Lendner, N Niethard, BA Mander… - Science …, 2023 - science.org
The proposed mechanisms of sleep-dependent memory consolidation involve the overnight
regulation of neural activity at both synaptic and whole-network levels. Now, there is a lack …