Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Small RNA molecules have an important role in gene regulation and RNA silencing therapy,
but it is challenging to detect these molecules without the use of time-consuming radioactive …

Solid-state nanopores are sensors capable of analysing individual unlabelled DNA
molecules in solution. Although the critical information obtained from nanopores (for …

Nanopores bear great potential as sensors for single molecules, which are detected as
resistive pulses in a simple electrical measurement. The investigation of proteins requires …

Proteins are structurally dynamic macromolecules, and it is challenging to quantify the
conformational properties of their native state in solution. Nanopores can be efficient tools to …

The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

The capability to screen a range of proteins at the single-molecule level with enhanced
selectivity in biological fluids has been in part a driving force in develo** future diagnostic …

Nucleic acid detection methods are crucial for many fields such as pathogen detection and
genoty**. Solid-state nanopore sensors represent a promising platform for nucleic acid …

We report the formation of solid-state nanopores using a scanning helium ion microscope.
The fabrication process offers the advantage of high sample throughput along with fine …