Periods of synchronized myelin changes shape brain function and plasticity
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …
support to axons, is conventionally thought of as a static structure that is set early in …
[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
Myelination generates aberrant ultrastructure that is resolved by microglia
To enable rapid propagation of action potentials, axons are ensheathed by myelin, a
multilayered insulating membrane formed by oligodendrocytes. Most of the myelin is …
multilayered insulating membrane formed by oligodendrocytes. Most of the myelin is …
Glia as sculptors of synaptic plasticity
Glial cells are non-neuronal cells in the nervous system that are crucial for proper brain
development and function. Three major classes of glia in the central nervous system (CNS) …
development and function. Three major classes of glia in the central nervous system (CNS) …
On myelinated axon plasticity and neuronal circuit formation and function
Studies of activity-driven nervous system plasticity have primarily focused on the gray matter.
However, MRI-based imaging studies have shown that white matter, primarily composed of …
However, MRI-based imaging studies have shown that white matter, primarily composed of …
Oligodendrocytes: myelination, plasticity, and axonal support
The myelination of axons has evolved to enable fast and efficient transduction of electrical
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …
Myelinated axon physiology and regulation of neural circuit function
The study of structural and functional plasticity in the central nervous system (CNS) to date
has focused primarily on that of neurons and synapses. However, more recent studies …
has focused primarily on that of neurons and synapses. However, more recent studies …
Myelin development, plasticity, and pathology in the auditory system
Myelin allows for the rapid and precise timing of action potential propagation along neuronal
circuits and is essential for healthy auditory system function. In this article, we discuss what …
circuits and is essential for healthy auditory system function. In this article, we discuss what …
White matter plasticity keeps the brain in tune: axons conduct while glia wrap
Precise timing of neuronal inputs is crucial for brain circuit function and development, where
it contributes critically to experience-dependent plasticity. Myelination therefore provides an …
it contributes critically to experience-dependent plasticity. Myelination therefore provides an …
Voluntary wheel exercise ameliorates cognitive impairment, hippocampal neurodegeneration and microglial abnormalities preceded by demyelination in a male …
H Zhuang, Q Li, C Sun, D Xu, G Gan, C Zhang… - Brain, Behavior, and …, 2023 - Elsevier
Acquired peripheral hearing loss (APHL) in midlife has been identified as the greatest
modifiable risk factor for dementia; however, the pathophysiological neural mechanisms …
modifiable risk factor for dementia; however, the pathophysiological neural mechanisms …