Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Recent advances in tumor targeting via EPR effect for cancer treatment

MA Subhan, SSK Yalamarty, N Filipczak… - Journal of personalized …, 2021 - mdpi.com
Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

JG Croissant, KS Butler, JI Zink, CJ Brinker - Nature Reviews Materials, 2020 - nature.com
Natural silica and silicates are predominantly crystalline and constitute the most abundant
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …

Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Mesoporous silica nanoparticles for drug delivery

M Manzano, M Vallet‐Regí - Advanced functional materials, 2020 - Wiley Online Library
In recent years, nanomedicine has emerged at the forefront of nanotechnology, generating
great expectations in the biomedical field. Researchers are develo** novel nanoparticles …

Nanoarchitectured structure and surface biofunctionality of mesoporous silica nanoparticles

RK Kankala, YH Han, J Na, CH Lee, Z Sun… - Advanced …, 2020 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs), one of the important porous materials, have
garnered interest owing to their highly attractive physicochemical features and …

Molecular engineering to boost AIE‐active free radical photogenerators and enable high‐performance photodynamic therapy under hypoxia

Q Wan, R Zhang, Z Zhuang, Y Li… - Advanced Functional …, 2020 - Wiley Online Library
The severe hypoxia in solid tumors and the vicious aggregation‐caused fluorescence
quenching (ACQ) of conventional photosensitizers (PSs) have limited the application of …

Nanoparticle-based drug delivery systems for cancer therapy

Y Dang, J Guan - Smart Materials in Medicine, 2020 - Elsevier
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …

Mesoporous silica nanoparticles: A comprehensive review on synthesis and recent advances

R Narayan, UY Nayak, AM Raichur, S Garg - Pharmaceutics, 2018 - mdpi.com
Recent advancements in drug delivery technologies utilizing a variety of carriers have
resulted in a path-breaking revolution in the approach towards diagnosis and therapy alike …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …