Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Inflammasomes in tissue damages and immune disorders after trauma
P Bortolotti, E Faure, E Kipnis - Frontiers in immunology, 2018 - frontiersin.org
Trauma remains a leading cause of death worldwide. Hemorrhagic shock and direct injury to
vital organs are responsible for early mortality whereas most delayed deaths are secondary …
vital organs are responsible for early mortality whereas most delayed deaths are secondary …
Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome
Y Zhang, X Li, JJ Grailer, N Wang… - Journal of pineal …, 2016 - Wiley Online Library
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are clinically severe
respiratory disorders, and there are currently no Food and Drug Administration–approved …
respiratory disorders, and there are currently no Food and Drug Administration–approved …
Reactive oxygen species at the crossroads of inflammasome and inflammation
A Harijith, DL Ebenezer, V Natarajan - Frontiers in physiology, 2014 - frontiersin.org
Inflammasomes form a crucial part of the innate immune system. These are multi-protein
oligomer platforms that are composed of intracellular sensors which are coupled with …
oligomer platforms that are composed of intracellular sensors which are coupled with …
Critical role for the NLRP3 inflammasome during acute lung injury
JJ Grailer, BA Canning, M Kalbitz… - The journal of …, 2014 - journals.aai.org
The inflammasome is a key factor in innate immunity and senses soluble pathogen and
danger-associated molecular patterns as well as biological crystals (urate, cholesterol, etc.) …
danger-associated molecular patterns as well as biological crystals (urate, cholesterol, etc.) …
Inflammatory caspases drive pyroptosis in acute lung injury
B Liu, R He, L Zhang, B Hao, W Jiang… - Frontiers in …, 2021 - frontiersin.org
Acute lung injury (ALI), a critical respiratory disorder that causes diffuse alveolar injury leads
to high mortality rates with no effective treatment. ALI is characterized by varying degrees of …
to high mortality rates with no effective treatment. ALI is characterized by varying degrees of …
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury
Mechanical ventilation of lungs is capable of activating the innate immune system and
inducing sterile inflammatory response. The proinflammatory cytokine IL-1β is among the …
inducing sterile inflammatory response. The proinflammatory cytokine IL-1β is among the …
Processes of sterile inflammation
Sterile inflammation occurs in acute conditions, such as ischemia reperfusion injury and
crystal-induced arthritis, as well as with chronic diseases, such as particle-induced lung …
crystal-induced arthritis, as well as with chronic diseases, such as particle-induced lung …
[HTML][HTML] New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease
Inflammasomes are large macromolecular signaling complexes that control the proteolytic
activation of two highly proinflammatory IL-1 family cytokines, IL-1β and IL-18. The NLRP3 …
activation of two highly proinflammatory IL-1 family cytokines, IL-1β and IL-18. The NLRP3 …
Role of monocytes and macrophages in regulating immune response following lung transplantation
S Chiu, A Bharat - Current opinion in organ transplantation, 2016 - journals.lww.com
Monocytes and macrophages are emerging as key players in mediating both the pathogen
response and sterile lung inflammation, including that arising from barotrauma and ischemia …
response and sterile lung inflammation, including that arising from barotrauma and ischemia …