ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …

SARS‐CoV‐2 is responsible for a disruptive worldwide viral pandemic, and renders a
severe respiratory disease known as COVID‐19. Spike protein of SARS‐CoV‐2 mediates …

Protein expression from stably transfected Chinese hamster ovary (CHO) clones is an
established but time‐consuming method for manufacturing therapeutic recombinant …

We report on the development of surface plasmon resonance (SPR) sensors and matching
ELISAs for the detection of nucleocapsid and spike antibodies specific against the novel …

Sensitive and specific serology tests are essential for epidemiological and public health
studies of COVID-19 and for vaccine efficacy testing. The presence of antibodies to SARS …

Virus-like particles (VLPs) constitute a promising approach to recombinant vaccine
development. They are robust, safe, versatile and highly immunogenic supra-molecular …

SARS-CoV-2 receptor binding domain (RBD) recognizes the angiotensin converting
enzyme 2 (ACE2) receptor in host cells that enables infection. Due to its antigenic specificity …

Reliable diagnosis is critical to identify infections of SARS-CoV-2 as well as to evaluate the
immune response to virus and vaccines. Consequently, it becomes crucial the isolation of …

The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
has had a profound impact on the global health and economy. While mass vaccination for …

A vaccine candidate to SARS-CoV-2 was constructed by coupling the viral receptor binding
domain (RBD) to the surface of the papaya mosaic virus (PapMV) nanoparticle (nano) to …