Engineering complexity in human tissue models of cancer

K Ronaldson-Bouchard, I Baldassarri… - Advanced drug delivery …, 2022 - Elsevier
Major progress in the understanding and treatment of cancer have tremendously improved
our knowledge of this complex disease and improved the length and quality of patients' …

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ‐on‐Chip Platform

DN Tavakol, TR Nash, Y Kim, PL Graney… - Advanced …, 2024 - Wiley Online Library
Galactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during
missions to the Moon and Mars. Experimental models capable of recapitulating human …

An engineered model of metastatic colonization of human bone marrow reveals breast cancer cell remodeling of the hematopoietic niche

I Baldassarri, DN Tavakol, PL Graney… - Proceedings of the …, 2024 - pnas.org
Incomplete understanding of metastatic disease mechanisms continues to hinder effective
treatment of cancer. Despite remarkable advancements toward the identification of …

Emerging trajectories for next generation tissue engineers

DN Tavakol, S Fleischer, T Falcucci… - ACS biomaterials …, 2021 - ACS Publications
The field of tissue engineering has evolved from its early days of engineering tissue
substitutes to current efforts at building human tissues for regenerative medicine and …

Looking on the horizon; potential and unique approaches to develo** radiation countermeasures for deep space travel

RS Bokhari, A Beheshti, SE Blutt, DE Bowles… - Life Sciences in Space …, 2022 - Elsevier
Future lunar missions and beyond will require new and innovative approaches to radiation
countermeasures. The Translational Research Institute for Space Health (TRISH) is focused …