Opposite interplay between the canonical WNT/β-catenin pathway and PPAR gamma: a potential therapeutic target in gliomas
A Vallée, Y Lecarpentier, R Guillevin, JN Vallée - Neuroscience bulletin, 2018 - Springer
In gliomas, the canonical Wingless/Int (WNT)/β-catenin pathway is increased while
peroxisome proliferator-activated receptor gamma (PPAR-γ) is downregulated. The two …
peroxisome proliferator-activated receptor gamma (PPAR-γ) is downregulated. The two …
m6A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling
JW **e, XB Huang, QY Chen, YB Ma, YJ Zhao, LC Liu… - Molecular cancer, 2020 - Springer
Background BATF2, also known as SARI, has been implicated in tumor progression.
However, its role, underlying mechanisms, and prognostic significance in human gastric …
However, its role, underlying mechanisms, and prognostic significance in human gastric …
Dysfunction of hair follicle mesenchymal progenitors contributes to age-associated hair loss
Skin aging is accompanied by hair loss due to impairments in hair follicle (HF) epithelial
progenitor cells and their mesenchymal niche. This inductive mesenchyme, called dermal …
progenitor cells and their mesenchymal niche. This inductive mesenchyme, called dermal …
RETRACTED ARTICLE: SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin
L Dai, X Cui, X Zhang, L Cheng, Y Liu, Y Yang… - Nature …, 2016 - nature.com
SARI, also called as BATF2, belongs to the BATF family and has been implicated in cancer
cell growth inhibition. However, the role and mechanism of SARI in tumour angiogenesis are …
cell growth inhibition. However, the role and mechanism of SARI in tumour angiogenesis are …
Matrix reloaded: CCN, tenascin and SIBLING group of matricellular proteins in orchestrating cancer hallmark capabilities
Matricellular proteins (MCPs) are the non-structural extracellular matrix (ECM) proteins with
various regulatory functions. MCPs are critical regulators of ECM homeostasis and are often …
various regulatory functions. MCPs are critical regulators of ECM homeostasis and are often …
Nuclear export of BATF2 enhances colorectal cancer proliferation through binding to CRM1
J Zhou, Z Lei, J Chen, S Liao, Y Chen… - Clinical and …, 2023 - Wiley Online Library
Background During the tumourigenesis and development of colorectal cancer (CRC), the
inactivation of tumour suppressor genes is closely involved, although detailed molecular …
inactivation of tumour suppressor genes is closely involved, although detailed molecular …
Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages
H Kanemaru, F Yamane, K Fukushima… - Proceedings of the …, 2017 - National Acad Sciences
The development of effective treatments against cancers is urgently needed, and the
accumulation of CD8+ T cells within tumors is especially important for cancer prognosis …
accumulation of CD8+ T cells within tumors is especially important for cancer prognosis …
BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells
X Zhang, Y Liu, L Dai, G Shi, J Deng, Q Luo, Q **e… - Oncogene, 2021 - nature.com
The basic leucine zipper ATF-like transcription factor 2 (BATF2) has been implicated in
inflammatory responses and anti-tumour effects. Little, however, is known regarding its …
inflammatory responses and anti-tumour effects. Little, however, is known regarding its …
BATF2 deficiency promotes progression in human colorectal cancer via activation of HGF/MET signaling: a potential rationale for combining MET inhibitors with IFNs
Z Liu, P Wei, Y Yang, W Cui, B Cao, C Tan, B Yu… - Clinical Cancer …, 2015 - AACR
Purpose: BATF2, a novel IFN-stimulated gene, inhibits tumor cell proliferation, invasion, and
migration. The objectives of this study were to determine how BATF2 expression is …
migration. The objectives of this study were to determine how BATF2 expression is …
Targeted demethylation of the SARI promotor impairs colon tumour growth
Q Wang, L Dai, Y Wang, J Deng, Y Lin, Q Wang… - Cancer letters, 2019 - Elsevier
SARI (suppressor of activator protein 1, regulated by IFN) functions as a tumour suppressor
and is inactivated in various cancers. However, the mechanism underlying SARI inactivation …
and is inactivated in various cancers. However, the mechanism underlying SARI inactivation …