Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …

The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has
been studied extensively using various methods, such as case‐control, candidate gene and …

In humans, genetic factors have long been suspected to contribute to the onset and outcome
of tuberculosis. Such effects are difficult to identify owing to their complex inheritance, and to …

The historical impression that tuberculosis was an inherited disorder has come full circle and
substantial evidence now exists of the human genetic contribution to susceptibility to …

Susceptibility to infectious diseases is influenced by genetic background and efficient
cellular immune activation is responsible for protection. In tuberculosis (TB), interferon …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is an infectious disease in
humans killing nearly three million people and eight million cases annually. The cytokines …

Background Cytokines play important roles in antiviral action. We examined whether
polymorphisms of IFN-γ, TNF-α and IL-10 affect the susceptibility to and outcome of severe …

Polymorphisms in the cytokine genes are known to influence cytokine levels and may be
associated with outcome of infections. We investigated the polymorphisms in the cytokine …

Variants of transcription factor binding sites (TFBSs) constitute an important part of the
human genome. Current evidence demonstrates close links between nucleotides within …

Background/Aims. Nucleotide diversity may affect the immune regulation of tuberculosis (TB)
patients, leading to the individual susceptibility to TB. In recent years, there are a lot of …