Animal toxins—Nature's evolutionary-refined toolkit for basic research and drug discovery

V Herzig, B Cristofori-Armstrong, MR Israel… - Biochemical …, 2020 - Elsevier
Venomous animals have evolved toxins that interfere with specific components of their
victim's core physiological systems, thereby causing biological dysfunction that aids in prey …

Spider venom: components, modes of action, and novel strategies in transcriptomic and proteomic analyses

N Langenegger, W Nentwig, L Kuhn-Nentwig - Toxins, 2019 - mdpi.com
This review gives an overview on the development of research on spider venoms with a
focus on structure and function of venom components and techniques of analysis. Major …

Natural products, their derivatives, mimics and synthetic equivalents: role in agrochemical discovery

TC Sparks, DR Hahn, NV Garizi - Pest management science, 2017 - Wiley Online Library
Natural products (NPs) have a long history as a source of, and inspiration for, novel
agrochemicals. Many of the existing herbicides, fungicides, and insecticides have their …

Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery

SD Robinson, EAB Undheim… - Expert review of …, 2017 - Taylor & Francis
Introduction: Animal venoms are complex chemical arsenals. Most venoms are rich in
bioactive peptides with proven potential as research tools, drug leads and drugs. Areas …

[HTML][HTML] Strategies for heterologous expression, synthesis, and purification of animal venom toxins

E Rivera-de-Torre, C Rimbault, TP Jenkins… - … in bioengineering and …, 2022 - frontiersin.org
Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …

Dangerous arachnids—Fake news or reality?

TJ Hauke, V Herzig - Toxicon, 2017 - Elsevier
The public perception of spiders and scorpions is skewed towards the potential harm they
can inflict in humans, despite recent scientific evidence that arachnid venom components …

Versatile spider venom peptides and their medical and agricultural applications

NJ Saez, V Herzig - Toxicon, 2019 - Elsevier
Spiders have been evolving complex and diverse repertoires of peptides in their venoms
with vast pharmacological activities for more than 300 million years. Spiders use their …

Tying pest insects in knots: the deployment of spider‐venom‐derived knottins as bioinsecticides

GF King - Pest management science, 2019 - Wiley Online Library
Spider venoms are complex chemical arsenals that contain a rich variety of insecticidal
toxins. However, the major toxin class in many spider venoms is disulfide‐rich peptides …

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

AA Walker, ML Mayhew, J **, V Herzig… - Nature …, 2018 - nature.com
The assassin bug venom system plays diverse roles in prey capture, defence and extra-oral
digestion, but it is poorly characterised, partly due to its anatomical complexity. Here we …

Diversity of peptide toxins from stinging ant venoms

SR Aili, A Touchard, P Escoubas, MP Padula, J Orivel… - Toxicon, 2014 - Elsevier
Abstract Ants (Hymenoptera: Formicidae) represent a taxonomically diverse group of
arthropods comprising nearly 13,000 extant species. Sixteen ant subfamilies have …