The lysyl oxidase family comprises five members in mammals, lysyl oxidase (LOX) and four
lysyl oxidase like proteins (LOXL1-4). They are copper amine oxidases with a highly …

On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

The field of mechanically interlocked molecules (MIMs) has advanced rapidly in recent
years, with much work focused on their use in materials, sensing, and catalysis. However …

Copper ions play various roles in mammalian cells, presumably due to their involvement in
different enzymatic reactions. Some studies indicated that serum copper correlates with …

In mammalian cells, histone deacetylase (HDAC) and Sirtuin (SIRT) are two families
responsible for removing acetyl groups from acetylated proteins. Here, we describe protein …

Among the thousands of known three-dimensional protein folds, only a few have been found
whose backbones are in knotted configurations. The rarity of knotted proteins has important …

Lysyl oxidases (LOXs), a type of copper-and lysyl tyrosylquinone (LTQ)-dependent amine
oxidase, catalyze the oxidative deamination of lysine residues of extracellular matrix (ECM) …

A growing number of organisms have been discovered inhabiting extreme environments,
including temperatures in excess of 100° C. How cellular proteins from such organisms …

Two series of novel LOXL2 enzyme inhibitors are described: benzylamines substituted with
electron withdrawing groups at the para-position and 2-substituted pyridine-4 …

This review will focus on how X-ray crystallographic studies of copper-containing amine
oxidases have complemented the solution, kinetic, and spectroscopic research on this …