Morbidity and mortality after major liver resection in patients with perihilar cholangiocarcinoma: a systematic review and meta-analysis

LC Franken, AM Schreuder, E Roos, S van Dieren… - Surgery, 2019 - Elsevier
Background Morbidity and mortality after hepatectomy for perihilar cholangiocarcinoma are
known to be high. However, reported postoperative outcomes vary, with notable differences …

Modern work-up and extended resection in perihilar cholangiocarcinoma: the AMC experience

F Rassam, E Roos, KP Van Lienden… - … archives of surgery, 2018 - Springer
Aim Perihilar cholangiocarcinoma (PHC) is a challenging disease and requires aggressive
surgical treatment in order to achieve curation. The assessment and work-up of patients with …

Perihilar cholangiocarcinoma–novel benchmark values for surgical and oncological outcomes from 24 expert centers

M Mueller, E Breuer, T Mizuno, F Bartsch, F Ratti… - Annals of …, 2021 - journals.lww.com
Objective: The aim of this study was to define robust benchmark values for the surgical
treatment of perihilar cholangiocarcinomas (PHC) to enable unbiased comparisons …

[HTML][HTML] High mortality after ALPPS for perihilar cholangiocarcinoma: case-control analysis including the first series from the international ALPPS registry

PB Olthof, RJS Coelen, JK Wiggers, BG Koerkamp… - HPB, 2017 - Elsevier
Introduction Resection of perihilar cholangiocarcinoma (PHC) entails high-risk surgery with
postoperative mortality reported up to 18%, even in specialized centers. The aim of this …

Liver resection for cancer: New developments in prediction, prevention and management of postresectional liver failure

KMC van Mierlo, FG Schaap, CHC Dejong… - Journal of …, 2016 - Elsevier
Hepatic failure is a feared complication that accounts for up to 75% of mortality after
extensive liver resection. Despite improved perioperative care, the increasing complexity …

Postoperative liver failure risk score: identifying patients with resectable perihilar cholangiocarcinoma who can benefit from portal vein embolization

PB Olthof, JK Wiggers, BG Koerkamp… - Journal of the American …, 2017 - Elsevier
Background Major liver resection for perihilar cholangiocarcinoma (PHC) is associated with
a 22% to 33% postoperative liver failure incidence. The aim of this study was analyze the …

Portal vein embolization is associated with reduced liver failure and mortality in high-risk resections for perihilar cholangiocarcinoma

PB Olthof, L Aldrighetti, R Alikhanov, M Cescon… - Annals of surgical …, 2020 - Springer
Background Preoperative portal vein embolization (PVE) is frequently used to improve future
liver remnant volume (FLRV) and to reduce the risk of liver failure after major liver resection …

[HTML][HTML] 99mTc-mebrofenin hepatobiliary scintigraphy predicts liver failure following major liver resection for perihilar cholangiocarcinoma

PB Olthof, RJS Coelen, RJ Bennink, M Heger, MF Lam… - HPB, 2017 - Elsevier
Background Posthepatectomy liver failure (PHLF) is a threatening complication after liver
surgery, especially in perihilar cholangiocarcinoma (PHC). This study aimed to assess the …

[HTML][HTML] Complications after liver surgery: a benchmark analysis

F Bagante, A Ruzzenente, EW Beal, T Campagnaro… - Hpb, 2019 - Elsevier
Background The best achievable short-term outcomes after liver surgery have not been
identified. Several factors may influence the post-operative course of patients undergoing …

[HTML][HTML] A comparison of treatment and outcomes of perihilar cholangiocarcinoma between Eastern and Western centers

PB Olthof, M Miyasaka, BG Koerkamp, JK Wiggers… - HPB, 2019 - Elsevier
Background Perihilar cholangiocarcinoma (PHC) often requires extensive surgery which is
associated with substantial morbidity and mortality. This study aimed to compare an Eastern …