Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
Development of frontal GABA and glutamate supports excitation/inhibition balance from adolescence into adulthood
Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …
Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex
Anxious individuals consistently fail in controlling emotional behavior, leading to excessive
avoidance, a trait that prevents learning through exposure. Although the origin of this failure …
avoidance, a trait that prevents learning through exposure. Although the origin of this failure …
Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls
There has been little analysis of neurochemical correlates of compulsive behaviour to
illuminate its underlying neural mechanisms. We use 7-Tesla proton magnetic resonance …
illuminate its underlying neural mechanisms. We use 7-Tesla proton magnetic resonance …
MRS-assessed brain GABA modulation in response to task performance and learning
Abstract Gamma-aminobutyric acid (GABA), the most important inhibitory neurotransmitter in
the human brain, has long been considered essential in human behavior in general and …
the human brain, has long been considered essential in human behavior in general and …
Adolescent maturation of dorsolateral prefrontal cortex glutamate: GABA and cognitive function is supported by dopamine-related neurobiology
Developmental changes in prefrontal cortex (PFC) excitatory (glutamatergic, Glu) and
inhibitory (gamma-aminobutryic acid, GABA) neurotransmitter balance (E: I) have been …
inhibitory (gamma-aminobutryic acid, GABA) neurotransmitter balance (E: I) have been …
Revealing the antiepileptic effect of α-asaronol on pentylenetetrazole-induced seizure rats using NMR-based metabolomics
X Zhao, L Liang, R Xu, P Cheng, P Jia, Y Bai… - ACS …, 2022 - ACS Publications
α-Asaronol from Acorus tatarinowii (known as “Shichangpu” in Traditional Chinese
medicine) has been proved to possess more efficient antiepileptic activity and lower toxicity …
medicine) has been proved to possess more efficient antiepileptic activity and lower toxicity …
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies
X **e, Y Shi, L Ma, W Yang, J Pu, Y Shen, Y Liu… - Journal of Affective …, 2023 - Elsevier
Background Numerous magnetic resonance spectroscopy (MRS) studies have reported
metabolic abnormalities in the brains of patients with depression, although inconsistent …
metabolic abnormalities in the brains of patients with depression, although inconsistent …
[HTML][HTML] Prefrontal excitation/inhibition balance supports adolescent enhancements in circuit signal to noise ratio
The development and refinement of neuronal circuitry allow for stabilized and efficient
neural recruitment, supporting adult-like behavioral performance. During adolescence, the …
neural recruitment, supporting adult-like behavioral performance. During adolescence, the …
Combining aperiodic 1/f slopes and brain simulation: An EEG/MEG proxy marker of excitation/inhibition imbalance in Alzheimer's disease
P Martínez‐Cañada, E Perez‐Valero… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Accumulation and interaction of amyloid‐beta (Aβ) and tau proteins during
progression of Alzheimer's disease (AD) are shown to tilt neuronal circuits away from …
progression of Alzheimer's disease (AD) are shown to tilt neuronal circuits away from …