[HTML][HTML] Genetics of attention deficit hyperactivity disorder

SV Faraone, H Larsson - Molecular psychiatry, 2019 - nature.com
Decades of research show that genes play an vital role in the etiology of attention deficit
hyperactivity disorder (ADHD) and its comorbidity with other disorders. Family, twin, and …

A copy number variation map of the human genome

M Zarrei, JR MacDonald, D Merico… - Nature reviews …, 2015 - nature.com
A major contribution to the genome variability among individuals comes from deletions and
duplications—collectively termed copy number variations (CNVs)—which alter the diploid …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

D Demontis, RK Walters, J Martin, M Mattheisen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan… - Nature …, 2013 - nature.com
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …

Artificial intelligence for precision medicine in neurodevelopmental disorders

M Uddin, Y Wang, M Woodbury-Smith - NPJ digital medicine, 2019 - nature.com
The ambition of precision medicine is to design and optimize the pathway for diagnosis,
therapeutic intervention, and prognosis by using large multidimensional biological datasets …

Molecular diagnostic yield of chromosomal microarray analysis and whole-exome sequencing in children with autism spectrum disorder

K Tammimies, CR Marshall, S Walker, G Kaur… - Jama, 2015 - jamanetwork.com
Importance The use of genome-wide tests to provide molecular diagnosis for individuals
with autism spectrum disorder (ASD) requires more study. Objective To perform …

Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

[LIBRO][B] The dyslexia debate

JG Elliott, EL Grigorenko - 2014 - books.google.com
The Dyslexia Debate examines how we use the term" dyslexia" and questions its efficacy as
a diagnosis. While many believe that a diagnosis of dyslexia will shed light on a reader's …

Genetic architecture in autism spectrum disorder

B Devlin, SW Scherer - Current opinion in genetics & development, 2012 - Elsevier
Autism spectrum disorder (ASD) is characterized by impairments in reciprocal social
interaction and communication, and by restricted and repetitive behaviors. Family studies …

Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing

Y Jiang, RKC Yuen, X **, M Wang, N Chen… - The American Journal of …, 2013 - cell.com
Autism Spectrum Disorder (ASD) demonstrates high heritability and familial clustering, yet
the genetic causes remain only partially understood as a result of extensive clinical and …