Medicinal herbs and many food ingredients possess favorable biological properties that
contribute to their therapeutic activities. One such natural product is betaine, a stable …

Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …

Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious
health problems worldwide. These two diseases have similar pathological spectra, ranging …

Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its
derivatives serve as components of structural lipoproteins, blood and membrane lipids, and …

Reactive oxygen species (ROS), products of oxidative stress, contribute to the initiation and
progression of the pathogenesis of various diseases. Glutathione is a major antioxidant that …

Background/Aims. Low serum folate levels can alter inflammatory reactions. Both
phenomena have been linked to Alzheimer's disease (AD), but the effect of folic acid on AD …

S-adenosyl-l-methionine (SAMe; AdoMet) is an important, metabolically pleiotropic molecule
that participates in multiple cellular reactions as the precursor for the synthesis of glutathione …

Nutrition science has evolved considerably in the past decade with new concepts and
discoveries. In response, advanced nutrition courses now encompass material on …

Background: Choline and betaine are found in a variety of plant and animal foods and were
recently shown to be associated with decreased homocysteine concentrations. Objective …