Intestinal metaplasia is a well-established premalignant condition of the stomach that is
characterized by mucin carbohydrate modifications defined by histochemical methods. The …

Mucinous differentiation is associated with both CpG island methylator phenotype and
microsatellite instability in colorectal cancer. The mucinous phenotype derives from …

Transmembrane mucins are glycoproteins involved in barrier function in epithelial tissues.
To identify novel transmembrane mucin genes, we performed a tblastn search of the …

We studied immunohistochemical expression of MUC1, MUC2, and MUC5AC in 194
carcinomas of different primary sites to determine whether differential expression patterns …

Background & Aims: Among the human mucin complementary DNAs thus far identified, two
(MUC5AC and MUC6) were cloned from stomach libraries. This study examines the …

Background & Aims: Secretory mucins play an important role in gastric cytoprotection and
are derived from a heterogeneous family of genes. The aim of this study was to determine …

BACKGROUND Although mucin expressions appear to be correlated with prognoses in
patients with various cancers, several studies have reported conflicting and inconclusive …

Publisher Summary This chapter focuses on mechanisms of alterations of Mucin-Associated
Antigens in gastrointestinal neoplasia and their implications in clinical diagnostic and …

In order to investigate the expression of MUC5AC mucin in normal gastric mucosa and
gastric carcinomas, we produced 3 monoclonal antibodies (MAbs) using a MUC5AC …

To investigate the expression of MUC6 mucin in gastric carcinomas, we generated a novel
monoclonal antibody (MAb CLH5) using an MUC6 synthetic peptide. MAb CLH5 reacted …