Xenobiotic metabolism and transport in Caenorhabditis elegans

JH Hartman, SJ Widmayer… - Journal of Toxicology …, 2021 - Taylor & Francis
Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …

Microbiome engineering: engineered live biotherapeutic products for treating human disease

JW Rutter, L Dekker, KA Owen… - … in Bioengineering and …, 2022 - frontiersin.org
The human microbiota is implicated in many disease states, including neurological
disorders, cancer, and inflammatory diseases. This potentially huge impact on human health …

Uncovering Nematicidal Natural Products from Xenorhabdus Bacteria

D Abebew, FS Sayedain, E Bode… - Journal of Agricultural …, 2022 - ACS Publications
Parasitic nematodes infect different species of animals and plants. Root-knot nematodes are
members of the genus Meloidogyne, which is distributed worldwide and parasitizes …

Single strain control of microbial consortia

AJH Fedorec, BD Karkaria, M Sulu… - Nature communications, 2021 - nature.com
The scope of bioengineering is expanding from the creation of single strains to the design of
microbial communities, allowing for division-of-labour, specialised sub-populations and …

Biosensors for point-of-care testing and personalized monitoring of gastrointestinal microbiota

L Ngashangva, S Chattopadhyay - Frontiers in Microbiology, 2023 - frontiersin.org
The gastrointestinal (GI) microbiota is essential in maintaining human health. Alteration of
the GI microbiota or gut microbiota (GM) from homeostasis (ie, dysbiosis) is associated with …

An engineered bacterial symbiont allows noninvasive biosensing of the honey bee gut environment

A Chhun, S Moriano-Gutierrez, F Zoppi, A Cabirol… - Plos …, 2024 - journals.plos.org
The honey bee is a powerful model system to probe host–gut microbiota interactions, and an
important pollinator species for natural ecosystems and for agriculture. While bacterial …

Characterization of eight bacterial biosensors for microbial diagnostic and therapeutic applications

TH Vaaben, R Vazquez-Uribe… - ACS Synthetic …, 2022 - ACS Publications
The engineering of microbial cells to produce and secrete therapeutics directly in the human
body, known as advanced microbial therapeutics, is an exciting alternative to current drug …

Engineering bacterial warriors: Harnessing microbes to modulate animal physiology

B Gao, D Ruiz, H Case, RE **kerson, Q Sun - Current opinion in …, 2024 - Elsevier
Highlights•Bacteria can modulate the physiology of multicellular organisms including
animals.•Engineered bacteria program model animal Caenorhabditis elegans' physiology.• …

C. elegans: A biosensor for host–microbe interactions

C Backes, D Martinez-Martinez, F Cabreiro - Lab Animal, 2021 - nature.com
Microbes are an integral part of life on this planet. Microbes and their hosts influence each
other in an endless dance that shapes how the meta-organism interacts with its …

Low-cost and cleanroom-free prototy** of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation

MA Mohd Asri, AN Nordin, N Ramli - Biomicrofluidics, 2021 - pubs.aip.org
Integrated microfluidic biosensors enable powerful microscale analyses in biology, physics,
and chemistry. However, conventional methods for fabrication of biosensors are dependent …