The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic

A Shariati, M Arshadi, MA Khosrojerdi… - Frontiers in public …, 2022 - frontiersin.org
For around three decades, the fluoroquinolone (FQ) antibiotic ciprofloxacin has been used
to treat a range of diseases, including chronic otorrhea, endocarditis, lower respiratory tract …

Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

Melimine-modified 3D-printed polycaprolactone scaffolds for the prevention of biofilm-related biomaterial infections

S Cometta, RT Jones, A Juárez-Saldivar, BC Donose… - ACS …, 2022 - ACS Publications
Biomaterial-associated infections are one of the major causes of implant failure. These
infections result from persistent bacteria that have adhered to the biomaterial surface before …

Chitosan derivatives-based films as pH-sensitive drug delivery systems with enhanced antioxidant and antibacterial properties

S Affes, I Aranaz, N Acosta, Á Heras, M Nasri… - International Journal of …, 2021 - Elsevier
The purpose of this study was to develop and characterize chitosan (Ch)-based films
incorporated with varying molecular weight (Mw) and acetylation degree (AD) chitosan …

Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: A review

WY Belay, M Getachew, BA Tegegne… - Frontiers in …, 2024 - frontiersin.org
Antibacterial drug resistance poses a significant challenge to modern healthcare systems,
threatening our ability to effectively treat bacterial infections. This review aims to provide a …

In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

S Masihzadeh, M Amin, Z Farshadzadeh - BMC microbiology, 2023 - Springer
Background The global crisis of antibiotic resistance increases the demand for the novel
promising alternative drugs such as antimicrobial peptides (AMPs). Here, the antibiofilm …

Antibacterial and Antibiofilm Activities of Novel Cyclic Peptides against Methicillin-Resistant Staphylococcus aureus

G Wei, Y He - International Journal of Molecular Sciences, 2022 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) has led to serious infections, especially
in hospitals and clinics, where treatment and prevention have become more difficult due to …

Enhancement of Antibiofilm Activity of Ciprofloxacin against Staphylococcus aureus by Administration of Antimicrobial Peptides

M Yasir, D Dutta, MDP Willcox - Antibiotics, 2021 - mdpi.com
Staphylococcus aureus can develop resistance by mutation, transfection or biofilm
formation. Resistance was induced in S. aureus by growth in sub-inhibitory concentrations of …

Drug loaded 3D-printed poly (ε-caprolactone) scaffolds for local antibacterial or anti-inflammatory treatment in bone regeneration

M Stepanova, I Averianov, I Gofman, N Shevchenko… - Polymers, 2023 - mdpi.com
Annual bone grafting surgeries due to bone fractures, resections of affected bones, skeletal
anomalies, osteoporosis, etc. exceed two million worldwide. In this regard, the creation of …