Towards an understanding of psychedelic-induced neuroplasticity
Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …
Psychedelics, mystical experience, and therapeutic efficacy: A systematic review
The mystical experience is a potential psychological mechanism to influence outcome in
psychedelic therapy. It includes features such as oceanic boundlessness, ego dissolution …
psychedelic therapy. It includes features such as oceanic boundlessness, ego dissolution …
Single-dose psilocybin treatment for major depressive disorder: a randomized clinical trial
Importance Psilocybin shows promise as a treatment for major depressive disorder (MDD).
Objective To evaluate the magnitude, timing, and durability of antidepressant effects and …
Objective To evaluate the magnitude, timing, and durability of antidepressant effects and …
Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up
Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …
substantial and rapid antidepressant effects in patients with major depressive disorder …
Psychedelic therapy for depressive symptoms: A systematic review and meta-analysis
Background Psychedelic therapy shows promise for Major Depressive Disorder, especially
when treatment-resistant, as well as life-threatening illness distress. The objective of this …
when treatment-resistant, as well as life-threatening illness distress. The objective of this …
Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants
W Duan, D Cao, S Wang, J Cheng - Chemical Reviews, 2023 - ACS Publications
Psychedelics make up a group of psychoactive compounds that induce hallucinogenic
effects by activating the serotonin 2A receptor (5-HT2AR). Clinical trials have demonstrated …
effects by activating the serotonin 2A receptor (5-HT2AR). Clinical trials have demonstrated …
Psilocybin-assisted therapy for major depressive disorder: An exploratory placebo-controlled, fixed-order trial
Background: Several early phase studies have demonstrated that psilocybin-assisted
therapy has rapid-acting and persisting antidepressant effects from just one or two doses …
therapy has rapid-acting and persisting antidepressant effects from just one or two doses …
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis
Y Yao, D Guo, TS Lu, FL Liu, SH Huang, MQ Diao… - Psychiatry …, 2024 - Elsevier
We aim to systematically review and meta-analyze the effectiveness and safety of
psychedelics [psilocybin, ayahuasca (active component DMT), LSD and MDMA] in treating …
psychedelics [psilocybin, ayahuasca (active component DMT), LSD and MDMA] in treating …
Psychedelic-assisted psychotherapy—a systematic review of associated psychological interventions
Modern clinical research on psychedelics is generating interesting outcomes in a wide array
of clinical conditions when psychedelic-assisted psychotherapy is delivered to appropriately …
of clinical conditions when psychedelic-assisted psychotherapy is delivered to appropriately …