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Early diagnosis of pancreatic cancer: challenges and new developments
Pancreatic cancer is a lethal malignancy with its incidence almost equivalent to mortality.
The complex pathophysiology, absence of early diagnostic and prognostic markers and …
The complex pathophysiology, absence of early diagnostic and prognostic markers and …
The peripheral-blood transcriptome: new insights into disease and risk assessment
S Mohr, CC Liew - Trends in molecular medicine, 2007 - cell.com
Future personalized medicine strategies for assessing an individual's health require, ideally,
a noninvasive system that is capable of integrating numerous interactive factors, including …
a noninvasive system that is capable of integrating numerous interactive factors, including …
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
Aging is a major risk factor for chronic disease in the human population, but there are little
human data on gene expression alterations that accompany the process. We examined …
human data on gene expression alterations that accompany the process. We examined …
Cell-type specific gene expression profiles of leukocytes in human peripheral blood
Background Blood is a complex tissue comprising numerous cell types with distinct functions
and corresponding gene expression profiles. We attempted to define the cell type specific …
and corresponding gene expression profiles. We attempted to define the cell type specific …
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells
ME Burczynski, RL Peterson, NC Twine… - The journal of molecular …, 2006 - Elsevier
Ulcerative colitis (UC) and Crohn's disease (CD) are common inflammatory bowel diseases
producing intestinal inflammation and tissue damage. Although emerging evidence …
producing intestinal inflammation and tissue damage. Although emerging evidence …
PBMCs: a new source of diagnostic and prognostic biomarkers
There are various types of molecular biomarkers that are derived from distinct starting
materials. Although many indirect biomarkers are found in blood, their detection remains a …
materials. Although many indirect biomarkers are found in blood, their detection remains a …
Assessing the validity of blood‐based gene expression profiles for the classification of schizophrenia and bipolar disorder: A preliminary report
MT Tsuang, N Nossova, T Yager… - American Journal of …, 2005 - Wiley Online Library
Recent advances have facilitated the use of blood‐derived RNA to conduct genomic
analyses of human diseases. This emerging technology represents a rigorous and …
analyses of human diseases. This emerging technology represents a rigorous and …
Comparison of different isolation techniques prior gene expression profiling of blood derived cells: impact on physiological responses, on overall expression and the …
S Debey, U Schoenbeck, M Hellmich… - The …, 2004 - nature.com
Owing to its clinical accessibility, peripheral blood is probably the best source for the
assessment of differences or changes in gene expression associated with disease or drug …
assessment of differences or changes in gene expression associated with disease or drug …
[HTML][HTML] Gene expression changes in children with autism
JP Gregg, L Lit, CA Baron, I Hertz-Picciotto, W Walker… - Genomics, 2008 - Elsevier
The objective of this study was to identify gene expression differences in blood differences in
children with autism (AU) and autism spectrum disorder (ASD) compared to general …
children with autism (AU) and autism spectrum disorder (ASD) compared to general …
Molecular characterization of breast cancer cell lines through multiple omic approaches
Background Breast cancer cell lines are frequently used as model systems to study the
cellular properties and biology of breast cancer. Our objective was to characterize a large …
cellular properties and biology of breast cancer. Our objective was to characterize a large …