Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE

HB Nguyen, AK Jaehne, N Jayaprakash, MW Semler… - Critical Care, 2016 - Springer
Prior to 2001 there was no standard for early management of severe sepsis and septic
shock in the emergency department. In the presence of standard or usual care, the …

Gender differences in critical illness and critical care research

TI Lat, MK McGraw, HD White - Clinics in chest medicine, 2021 - chestmed.theclinics.com
Research regarding the impact both social and genetic determinants of health play in
admission to the intensive care unit (ICU) and outcomes from an ICU stay have gained …

Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study

E Albrecht, P Taffe, B Yersin… - British journal of …, 2013 - academic.oup.com
Background Prehospital oligoanalgesia is prevalent among trauma victims, even when the
emergency medical services team includes a physician. We investigated if not only patients' …

Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation

HB Nguyen, WS Kuan, M Batech, P Shrikhande… - Critical care, 2011 - Springer
Abstract Introduction Implementation of the Surviving Sepsis Campaign (SSC) guidelines
has been associated with improved outcome in patients with severe sepsis. Resolution of …

Sex-based differences in ED management of critically ill patients with sepsis: a nationwide cohort study

J Sunden-Cullberg, A Nilsson, M Inghammar - Intensive care medicine, 2020 - Springer
Purpose To compare management and outcomes for critically ill women and men with
sepsis in the emergency medical services (EMS), the emergency department (ED) and the …

Determining delayed admission to the intensive care unit for mechanically ventilated patients in the emergency department

SC Hung, CT Kung, CW Hung, BM Liu, JW Liu, G Chew… - Critical Care, 2014 - Springer
Introduction The adverse effects of delayed admission to the intensive care unit (ICU) have
been recognized in previous studies. However, the definitions of delayed admission vary …

Prognosis of emergency department patients with suspected infection and intermediate lactate levels: a systematic review

MA Puskarich, BM Illich, AE Jones - Journal of critical care, 2014 - Elsevier
Purpose Previous studies have shown a correlation between blood lactate greater than 4.0
mmol/L and mortality in patients with suspected infection in the emergency department (ED) …

Initial management of pneumonia and sepsis: factors associated with improved outcome

R Menéndez, A Torres, S Reyes… - European …, 2011 - publications.ersnet.org
Processes of care and adherence to guidelines have been associated with improved
survival in community-acquired pneumonia (CAP). In sepsis, bundles of processes of care …

Nontraumatic hypotension and shock in the emergency department and the prehospital setting, prevalence, etiology, and mortality: a systematic review

JG Holler, CN Bech, DP Henriksen, S Mikkelsen… - PLoS …, 2015 - journals.plos.org
Background Acute patients presenting with hypotension in the prehospital or emergency
department (ED) setting are in need of focused management and knowledge of the …

Physician variation in time to antimicrobial treatment for septic patients presenting to the emergency department

ID Peltan, KH Mitchell, KE Rudd, BA Mann… - Critical care …, 2017 - journals.lww.com
Objectives: Delayed initiation of appropriate antimicrobials is linked to higher sepsis
mortality. We investigated interphysician variation in septic patients' door-to-antimicrobial …