Though totipotency and pluripotency are transient during early embryogenesis, they
establish the foundation for the development of all mammals. Studying these in vivo has …

Develo** functional organs from stem cells remains a challenging goal in regenerative
medicine. Existing methodologies, such as tissue engineering, bioprinting, and organoids …

Understanding the mechanisms of blastocyst formation and implantation is critical for
improving farm animal reproduction but is hampered by a limited supply of embryos. Here …

Early embryo development is a highly dynamic process that plays a crucial role in
determining the health and characteristics of an organism. For many years, embryonic and …

A central determinant of pregnancy success is proper development of the conceptus
(embryo/fetus and associated extraembryonic membranes including the placenta). Although …

Communication between the maternal endometrium and develo** embryo/conceptus is
critical to support successful pregnancy to term. Particularly studying the peri-implantation …

Trophoblast stem cells (TSCs) are a proliferative multipotent population derived from the
trophectoderm of the blastocyst, which will give rise to all the functional cell types of the …

Advances in three-dimensional culture technologies have facilitated the development of
synthetic embryo models, such as blastoids, through the co-culturing of diverse stem cell …

In vitro fertilization (IVF) is a widely used assisted reproductive technology to achieve a
successful pregnancy. However, the acquisition of oxidative stress in embryo in vitro culture …

Simple Summary A high incidence of early pregnancy failures exists in beef and dairy cows.
This review describes various problems which occur during early gestation that contribute to …