Horizontal transfer of antibiotic resistance genes in clinical environments

NA Lerminiaux, ADS Cameron - Canadian journal of …, 2019 - cdnsciencepub.com
A global medical crisis is unfolding as antibiotics lose effectiveness against a growing
number of bacterial pathogens. Horizontal gene transfer (HGT) contributes significantly to …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Acinetobacter baumannii: Emergence of a Successful Pathogen

AY Peleg, H Seifert, DL Paterson - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Diversity, epidemiology, and genetics of class D β-lactamases

L Poirel, T Naas, P Nordmann - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Class D β-lactamase-mediated resistance to β-lactams has been increasingly reported
during the last decade. Those enzymes also known as oxacillinases or OXAs are widely …

Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages

R Zarrilli, S Pournaras, M Giannouli… - International journal of …, 2013 - Elsevier
The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to
carbapenems and most or all available antibiotics during the last decade is a worrying …

Application of whole-genome sequencing for bacterial strain ty** in molecular epidemiology

SJ Salipante, DJ SenGupta, LA Cummings… - Journal of clinical …, 2015 - Am Soc Microbiol
Nosocomial infections pose a significant threat to patient health; however, the gold standard
laboratory method for determining bacterial relatedness (pulsed-field gel electrophoresis …

Mobile genetic elements in Acinetobacter antibiotic‐resistance acquisition and dissemination

HR Noel, JR Petrey, LD Palmer - … of the New York Academy of …, 2022 - Wiley Online Library
Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …

Resources for genetic and genomic analysis of emerging pathogen Acinetobacter baumannii

LA Gallagher, E Ramage, EJ Weiss… - Journal of …, 2015 - Am Soc Microbiol
Acinetobacter baumannii is a Gram-negative bacterial pathogen notorious for causing
serious nosocomial infections that resist antibiotic therapy. Research to identify factors …

Systematic detection of horizontal gene transfer across genera among multidrug-resistant bacteria in a single hospital

DR Evans, MP Griffith, AJ Sundermann, KA Shutt… - Elife, 2020 - elifesciences.org
Multidrug-resistant bacteria pose a serious health threat, especially in hospitals. Horizontal
gene transfer (HGT) of mobile genetic elements (MGEs) facilitates the spread of antibiotic …