The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Sigma factors provide promoter recognition specificity to RNA polymerase holoenzyme,
contribute to DNA strand separation, and then dissociate from the core enzyme following …

In Pseudomonas aeruginosa, as in most bacterial species, the expression of genes is tightly
controlled by a repertoire of transcriptional regulators, particularly the so-called sigma (σ) …

Antimicrobial agents target a range of extra-and/or intracellular loci from cytoplasmic wall to
membrane, intracellular enzymes and genetic materials. Meanwhile, many resistance …

Sigma factors are essential global regulators of transcription initiation in bacteria which
confer promoter recognition specificity to the RNA polymerase core enzyme. They provide …

Mycobacterium tuberculosis is a remarkable pathogen capable of adapting and surviving in
various harsh conditions. Correct gene expression regulation is essential for the success of …

Neisseria gonorrhoeae is a host-adapted pathogen that colonizes primarily the human
genitourinary tract. This bacterium encounters reactive oxygen and reactive nitrogen species …

A variety of mechanisms are used to signal extracytoplasmic conditions to the cytoplasm.
These mechanisms activate extracytoplasmic function (ECF) sigma factors which recruit …

In bacteria, DNA methylation can be facilitated by 'orphan'DNA methyltransferases lacking
cognate restriction endonucleases, but whether and how these enzymes control key cellular …

Summary Mycobacterium bovis Bacille Calmette–Guérin (BCG) strains are genetically and
phenotypically heterogeneous. Expression of the antigenic proteins MPB70 and MPB83 is …