Urinary tract infections: epidemiology, mechanisms of infection and treatment options

AL Flores-Mireles, JN Walker, M Caparon… - Nature reviews …, 2015 - nature.com
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range
of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus …

[HTML][HTML] Iron in infection and immunity

JE Cassat, EP Skaar - Cell host & microbe, 2013 - cell.com
Iron is an essential nutrient for both humans and pathogenic microbes. Because of its ability
to exist in one of two oxidation states, iron is an ideal redox catalyst for diverse cellular …

Urinary tract infection: pathogenesis and outlook

LK McLellan, DA Hunstad - Trends in molecular medicine, 2016 - cell.com
The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant
impact on millions of patients worldwide, most of whom are otherwise healthy women …

The battle for iron between bacterial pathogens and their vertebrate hosts

EP Skaar - PLoS pathogens, 2010 - journals.plos.org
Iron is a vital nutrient for virtually all forms of life. The requirement for iron is based on its role
in cellular processes ranging from energy generation and DNA replication to oxygen …

Proteus mirabilis and Urinary Tract Infections

JN Schaffer, MM Pearson - Urinary tract infections: Molecular …, 2017 - Wiley Online Library
Proteus mirabilis is well known in clinical laboratories and microbiology survey courses as
the species that swarms across agar surfaces, overtaking any other species present in the …

The emerging threat of multidrug-resistant Gram-negative bacteria in urology

HM Zowawi, PNA Harris, MJ Roberts… - Nature Reviews …, 2015 - nature.com
Antibiotic resistance in Gram-negative uropathogens is a major global concern. Worldwide,
the prevalence of Enterobacteriaceae that produce extended-spectrum β-lactamase or …

Urinary tract infection: Pathogenicity, antibiotic resistance and development of effective vaccines against Uropathogenic Escherichia coli

MRA Karam, M Habibi, S Bouzari - Molecular immunology, 2019 - Elsevier
Urinary tract infections (UTIs) are recognized as one of the most common infectious
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …

Host–pathogen interactions in urinary tract infection

GR Nielubowicz, HLT Mobley - Nature Reviews Urology, 2010 - nature.com
The urinary tract is a common site of bacterial infections; nearly half of all women experience
at least one urinary tract infection (UTI) during their lifetime. These infections are classified …

The nature of immune responses to urinary tract infections

SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …

Urinary Tract Infections Caused by Uropathogenic Escherichia coli: Mechanisms of Infection and Treatment Options

Y Zhou, Z Zhou, L Zheng, Z Gong, Y Li, Y **… - International journal of …, 2023 - mdpi.com
Urinary tract infections (UTIs) are common bacterial infections that represent a severe public
health problem. They are often caused by Escherichia coli (E. coli), Klebsiella pneumoniae …