Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

Background Age-related macular degeneration (AMD) is the leading cause of blindness in
Western countries. Numerous risk factors have been reported but the evidence and strength …

Introduction he human body has an elaborate system for managing and regulating the
amount of key trace metals circulating in blood and stored in cells. Nutrient metals from our …

The process of senescence (aging) is predominantly determined by the action of wild-type
genes. For most organisms, this does not reflect any adaptive function that senescence …

Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …

Lutein is a carotenoid with reported anti-inflammatory properties. A large body of evidence
shows that lutein has several beneficial effects, especially on eye health. In particular, lutein …

From the dawn of civilization, humanity has dreamed of immortality. So why didn't the
discovery of the anti-aging properties of mTOR inhibitors change the world forever? I will …

The endoplasmic reticulum (ER) is the major site of calcium storage and protein folding. It
has a unique oxidizing-folding environment due to the predominant disulfide bond formation …

Glutathione (GSH) and bilirubin are prominent endogenous antioxidant cytoprotectants.
Despite tissue levels that are thousands of times lower than GSH, bilirubin is effective …

Age‐related macular degeneration (AMD) is a common cause of visual impairment in the
elderly. There are very limited therapeutic options for AMD with the predominant therapies …