PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial

TB Dorff, MS Blanchard, LN Adkins, L Luebbert… - Nature medicine, 2024 - nature.com
Despite recent therapeutic advances, metastatic castration-resistant prostate cancer
(mCRPC) remains lethal. Chimeric antigen receptor (CAR) T cell therapies have …

[HTML][HTML] Liquid biopsy in urothelial carcinoma: Detection techniques and clinical applications

S Wu, R Li, Y Jiang, J Yu, J Zheng, Z Li, M Li… - Biomedicine & …, 2023 - Elsevier
The types of urothelial carcinoma (UC) include urothelial bladder cancer and upper tract
urothelial carcinoma. Current diagnostic techniques cannot meet the needs of patients …

[HTML][HTML] Modern kidney-sparing management of upper tract urothelial carcinoma

A Ghoreifi, R Sari Motlagh, G Fuchs - Cancers, 2023 - mdpi.com
Simple Summary Upper tract urothelial carcinoma (UTUC) is a lethal cancer of the urinary
tract. Radical nephroureterectomy with bladder cuff excision is the gold standard for the …

Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery

SN Shishido, E Lin, N Nissen, G Courcoubetis… - npj Precision …, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than 10%
due to its late diagnosis, rapid metastasis, and chemotherapeutic resistance. For a small …

Liquid biopsy approach to monitor the efficacy and response to CAR-T cell therapy

SN Shishido, O Hart, S Jeong… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Background Chimeric antigen receptor (CAR)-T cells are approved for use in the treatment
of hematological malignancies. Axicabtagene ciloleucel (YESCARTA) and brexucabtagene …

Determining the efficacy of ExThera Seraph100 blood filtration in patients diagnosed with pancreatic cancer through the liquid biopsy

SN Shishido, D Suresh, G Courcoubetis, B Ye, E Lin… - BJC reports, 2024 - nature.com
Background Cancer becomes lethal as it spreads from the primary site to the rest of the
body. Circulating tumor cells (CTCs) are biomarkers of disease progression and have been …

Segmental ureterectomy for high-risk ureteral carcinoma: a preliminary report

W Wei, J Liu, L Wang, X Duan, D Ding - BMC urology, 2023 - Springer
Background EAU guidelines strongly recommend kidney sparing surgery (KSS) as the
primary treatment option for the low-risk UTUC patients. While there are few reports …

[HTML][HTML] Defining a liquid biopsy profile of circulating tumor cells and oncosomes in metastatic colorectal cancer for clinical utility

S Narayan, G Courcoubetis, J Mason, A Naghdloo… - Cancers, 2022 - mdpi.com
Simple Summary Metastatic colorectal cancer (mCRC) is typified by its tumor heterogeneity
and changing disease states, suggesting that personalized medicine approaches could be …

Circulation of rare events in the liquid biopsy for early detection of lung mass lesions

K Resnick, A Shah, J Mason, P Kuhn, J Nieva… - Thoracic …, 2024 - Wiley Online Library
Background Lung cancer screening with low‐dose computed tomography (CT) scans
(LDCT) has reduced mortality for patients with high‐risk smoking histories, but it has …

A urine-based liquid biopsy for detection of upper tract urothelial carcinoma: a self-matched study

W Wei, P Fan, Z Zhang, D Wu, J Liu, L Wang, X Duan… - BMC cancer, 2024 - Springer
Background To establish the pathological diagnosis of UTUC before treatment is profitable.
At present, the conventional pathological diagnostic methods have certain problems …