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[HTML][HTML] Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis
Y Feng, M Spezia, S Huang, C Yuan, Z Zeng, L Zhang… - Genes & diseases, 2018 - Elsevier
As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …
formidable public health challenge on a global scale. Breast cancer consists of a group of …
Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies
A Marra, D Trapani, G Viale, C Criscitiello… - NPJ breast …, 2020 - nature.com
Triple-negative breast cancer (TNBC) is not a unique disease, encompassing multiple
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin
Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer
Rapidly proliferating tumor and immune cells need metabolic programs that support energy
and biomass production. The amino acid glutamine is consumed by effector T cells and …
and biomass production. The amino acid glutamine is consumed by effector T cells and …
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
Chemoresistance is a major obstacle in triple negative breast cancer (TNBC), the most
aggressive breast cancer subtype. Here we identify hypoxia-induced ECM re-modeler, lysyl …
aggressive breast cancer subtype. Here we identify hypoxia-induced ECM re-modeler, lysyl …
Pathology of triple negative breast cancer
F Borri, A Granaglia - Seminars in cancer biology, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …
Advances in the systemic treatment of triple-negative breast cancer
JM Lebert, R Lester, E Powell, M Seal, J McCarthy - Current oncology, 2018 - mdpi.com
Triple-negative breast cancer constitutes a heterogeneous group of malignancies that are
often aggressive and associated with a poor prognosis. Molecular characterization, while …
often aggressive and associated with a poor prognosis. Molecular characterization, while …
An overview of triple-negative breast cancer
P Kumar, R Aggarwal - Archives of gynecology and obstetrics, 2016 - Springer
Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …
comprising various breast cancers simply defined by the absence of estrogen receptor …
Triple-negative breast cancer: is there a treatment on the horizon?
Triple-negative breast cancer (TNBC), which accounts for 15–20% of all breast cancers,
does not express estrogen receptor (ER) or progesterone receptor (PR) and lacks human …
does not express estrogen receptor (ER) or progesterone receptor (PR) and lacks human …
[HTML][HTML] Genetic markers in triple-negative breast cancer
Z Sporikova, V Koudelakova, R Trojanec… - Clinical breast cancer, 2018 - Elsevier
Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancer cases and
is characterized by the absence of estrogen, progesterone, and human epidermal growth …
is characterized by the absence of estrogen, progesterone, and human epidermal growth …