Ruthenium complexes as anticancer agents: A brief history and perspectives

SY Lee, CY Kim, TG Nam - Drug design, development and therapy, 2020 - Taylor & Francis
Platinum (Pt)-based anticancer drugs such as cisplatin have been used to treat various
cancers. However, they have some limitations including poor selectivity and toxicity towards …

Ruthenium (II) complexes with dppz: from molecular photoswitch to biological applications

G Li, L Sun, L Ji, H Chao - Dalton Transactions, 2016 - pubs.rsc.org
The DNA photoswitch [Ru (bpy) 2dppz] 2+(bpy= 2, 2′-bipyridine, dppz= dipyrido [3, 2-a:
2′, 3′-c] phenazine) has attracted much attention and become a powerful tool for studying …

Recent Advances in Mitochondria‐Localized Luminescent Ruthenium (II) Metallodrugs as Anticancer Agents

SA Patra, G Sahu, S Das, R Dinda - ChemMedChem, 2023 - Wiley Online Library
Presently, the most effective way to transport drugs specifically to mitochondria inside the
cells is of pharmacophoric interest, as mitochondria are recognized as one of the most …

[Ru(Me4phen)2dppz]2+, a Light Switch for DNA Mismatches

AN Boynton, L Marcélis, JK Barton - Journal of the American …, 2016 - ACS Publications
[Ru (Me4phen) 2dppz] 2+ serves as a luminescent “light switch” for single base mismatches
in DNA. The preferential luminescence enhancement observed with mismatches results …

Ruthenium Complex “Light Switches” that are Selective for Different G‐Quadruplex Structures

E Wachter, D Moyá, S Parkin… - Chemistry–A European …, 2016 - Wiley Online Library
Recognition and regulation of G‐quadruplex nucleic acid structures is an important goal for
the development of chemical tools and medicinal agents. The addition of a bromo …

Ruthenium (II) complexes of saccharin with dipyridoquinoxaline and dipyridophenazine: Structures, biological interactions and photoinduced DNA damage activity

P Kumar, S Dasari, AK Patra - European Journal of Medicinal Chemistry, 2017 - Elsevier
Ruthenium complexes trans-[Ru (sac) 2 (dpq) 2](1) and trans-[Ru (sac) 2 (dppz) 2](2) where
sac is artificial sweetener saccharin (o-sulfobenzimide; 1, 2-benzothiazole-3 (2H)-one1, 1 …

Epitaxy: Programmable atom equivalents versus atoms

MX Wang, SE Seo, PA Gabrys… - Spherical Nucleic …, 2020 - api.taylorfrancis.com
The epitaxial deposition of thin films has been key to the semiconduct as a function of cry or
industry orientation from a substr stal in its structur efforts e. The tr to control ansf mat er of or …

Modulating the bond strength of DNA-nanoparticle superlattices

SE Seo, MX Wang, CM Shade, JL Rouge… - Spherical Nucleic …, 2020 - api.taylorfrancis.com
The ability to build complex, hierarchical materials with precise control over the identity and
placement e been a goal of xamples of self-assembled functional materials science [1] …

Ultrasensitive and Rapid Circulating Tumor DNA Liquid Biopsy Using Surface-Confined Gene Amplification on Dispersible Magnetic Nano-Electrodes

BC Park, JO Soh, HJ Choi, HS Park, SM Lee, HE Fu… - ACS …, 2024 - ACS Publications
Circulating tumor DNA (ctDNA) detection has been acknowledged as a promising liquid
biopsy approach for cancer diagnosis, with various ctDNA assays used for early detection …

Ru (II)-dppz derivatives and their interactions with DNA: Thirty years and counting

ML Di Pietro, G La Ganga, F Nastasi, F Puntoriero - Applied Sciences, 2021 - mdpi.com
Transition metal complexes with dppz-type ligands (dppz= dipyrido [3, 2-a: 2′, 3′-c]
phenazine) are extensively studied and attract a considerable amount of attention …