The Niemann-Pick type diseases–A synopsis of inborn errors in sphingolipid and cholesterol metabolism

FW Pfrieger - Progress in lipid research, 2023 - Elsevier
Disturbances of lipid homeostasis in cells provoke human diseases. The elucidation of the
underlying mechanisms and the development of efficient therapies represent formidable …

Ivermectin: From theory to clinical application

DS Ashour - International journal of antimicrobial agents, 2019 - Elsevier
Approximately 250 million people have been using ivermectin (IVM) annually to combat
many parasitic diseases including filariasis, onchocerciasis, strongyloidiasis, scabies and …

Oral, ultra–long-lasting drug delivery: application toward malaria elimination goals

AM Bellinger, M Jafari, TM Grant, S Zhang… - Science translational …, 2016 - science.org
Efforts at elimination of scourges, such as malaria, are limited by the logistic challenges of
reaching large rural populations and ensuring patient adherence to adequate …

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

C Chaccour, F Hammann, NR Rabinovich - Malaria Journal, 2017 - Springer
Ivermectin is an endectocide that has been used broadly in single dose community
campaigns for the control of onchocerciasis and lymphatic filariasis for more than 30 years …

Ivermectin susceptibility and sporontocidal effect in Greater Mekong Subregion Anopheles

KC Kobylinski, R Ubalee, A Ponlawat… - Malaria journal, 2017 - Springer
Background Novel vector control methods that can directly target outdoor malaria
transmission are urgently needed in the Greater Mekong Subregion (GMS) to accelerate …

Increasing the potential for malaria elimination by targeting zoophilic vectors

JL Waite, S Swain, PA Lynch, SK Sharma, MA Haque… - Scientific reports, 2017 - nature.com
Abstract Countries in the Asia Pacific region aim to eliminate malaria by 2030. A cornerstone
of malaria elimination is the effective management of Anopheles mosquito vectors. Current …

Administration of ivermectin to peridomestic cattle: a promising approach to target the residual transmission of human malaria

HS Pooda, JB Rayaisse, DFS Hien, T Lefèvre… - Malaria journal, 2015 - Springer
Background The success of current control tools in combatting malaria vectors is well
established. However, sustained residual transmission of Plasmodium parasites persists …

[HTML][HTML] Of genes and genomes: mosquito evolution and diversity

L Ruzzante, MJMF Reijnders, RM Waterhouse - Trends in parasitology, 2019 - cell.com
Mosquitoes are widely despised for their exasperating buzzing and irritating bites, and more
poignantly because, during blood-feeding, females may transmit pathogens that cause …

[HTML][HTML] Repeat ivermectin mass drug administrations for malaria control II: protocol for a double-blind, cluster-randomized, placebo-controlled trial for the integrated …

BD Foy, A Some, T Magalhaes, L Gray… - JMIR Research …, 2023 - researchprotocols.org
Background: The gains made against malaria have stagnated since 2015, threatened further
by increasing resistance to insecticides and antimalarials. Improvement in malaria control …

Endectocides as a complementary intervention in the malaria control program: a systematic review

FG Khaligh, A Jafari, E Silivanova, M Levchenko… - Systematic …, 2021 - Springer
Background Malaria is the most common vector-borne disease transmitted to humans by
Anopheles mosquitoes. Endectocides and especially ivermectin will be available as a vector …