Human strongyloidiasis: complexities and pathways forward

D Buonfrate, RS Bradbury, MR Watts… - Clinical Microbiology …, 2023 - Am Soc Microbiol
SUMMARY Strongyloidiasis is a World Health Organization neglected tropical disease
usually caused by Strongyloides stercoralis, a parasitic worm with a complex life cycle …

[HTML][HTML] New diagnostic tools in schistosomiasis

J Utzinger, SL Becker, L Van Lieshout… - Clinical microbiology …, 2015 - Elsevier
Schistosomiasis is a water-based parasitic disease that affects over 250 million people.
Control efforts have long been in vain, which is one reason why schistosomiasis is …

[HTML][HTML] Sensitivity of diagnostic tests for human soil-transmitted helminth infections: a meta-analysis in the absence of a true gold standard

B Nikolay, SJ Brooker, RL Pullan - International journal for parasitology, 2014 - Elsevier
Reliable, sensitive and practical diagnostic tests are an essential tool in disease control
programmes for map**, impact evaluation and surveillance. To provide a robust global …

[HTML][HTML] Novel approaches to the diagnosis of Strongyloides stercoralis infection

D Buonfrate, F Formenti, F Perandin, Z Bisoffi - Clinical Microbiology and …, 2015 - Elsevier
Strongyloides stercoralis differs from the other soil-transmitted helminths because it puts
infected subjects at risk of a fatal syndrome (in cases of immunosuppression for medical …

Application of a multiplex quantitative PCR to assess prevalence and intensity of intestinal parasite infections in a controlled clinical trial

S Llewellyn, T Inpankaew, SV Nery… - PLoS neglected …, 2016 - journals.plos.org
Background Accurate quantitative assessment of infection with soil transmitted helminths
and protozoa is key to the interpretation of epidemiologic studies of these parasites, as well …

Accuracy of molecular biology techniques for the diagnosis of Strongyloides stercoralis infection—A systematic review and meta-analysis

D Buonfrate, A Requena-Mendez… - PLoS neglected …, 2018 - journals.plos.org
Background Strongyloides stercoralis infection is a neglected tropical disease which can
lead to severe symptoms and even death in immunosuppressed people. Unfortunately, its …

Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass …

AV Easton, RG Oliveira, EM O'Connell, S Kepha… - Parasites & vectors, 2016 - Springer
Background Although chronic morbidity in humans from soil transmitted helminth (STH)
infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it …

Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in …

P Cools, J Vlaminck, M Albonico, S Ame… - PLoS neglected …, 2019 - journals.plos.org
Background Because the success of deworming programs targeting soil-transmitted
helminths (STHs) is evaluated through the periodically assessment of prevalence and …

Improved PCR-based detection of soil transmitted helminth infections using a next-generation sequencing approach to assay design

N Pilotte, M Papaiakovou, JR Grant… - PLoS neglected …, 2016 - journals.plos.org
Background The soil transmitted helminths are a group of parasitic worms responsible for
extensive morbidity in many of the world's most economically depressed locations. With …

[HTML][HTML] Molecular diagnostics for soil-transmitted helminths

EM O'Connell, TB Nutman - The American journal of tropical …, 2016 - ncbi.nlm.nih.gov
Historically, the diagnosis of soil-transmitted helminths (STHs)(eg, Strongyloides stercoralis,
Trichuris trichiura, Ancylostoma duodenale, Necator americanus, and Ascaris lumbricoides) …