Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

W Chen, M Schilperoort, Y Cao, J Shi, I Tabas… - Nature Reviews …, 2022 - nature.com
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

[HTML][HTML] Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular …

Q Zhang, J Liu, H Duan, R Li, W Peng, C Wu - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Recently, Nrf2/HO-1 has received extensive attention as the main
regulatory pathway of intracellular defense against oxidative stress and is considered an …

Mechanistic insights into the oxidized low‐density lipoprotein‐induced atherosclerosis

C Khatana, NK Saini, S Chakrabarti… - Oxidative medicine …, 2020 - Wiley Online Library
Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …

Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits

NN Mahleyuddin, S Moshawih, LC Ming, HH Zulkifly… - Molecules, 2021 - mdpi.com
Coriandrum sativum (C. sativum), belonging to the Apiaceae (Umbelliferae) family, is widely
recognized for its uses in culinary and traditional medicine. C. sativum contains various …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

[HTML][HTML] Diabetes mellitus—Progress and opportunities in the evolving epidemic

ED Abel, AL Gloyn, C Evans-Molina, JJ Joseph… - Cell, 2024 - cell.com
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …

Omega-3 fatty acids and inflammatory processes: from molecules to man

PC Calder - Biochemical Society Transactions, 2017 - portlandpress.com
Inappropriate, excessive or uncontrolled inflammation contributes to a range of human
diseases. Inflammation involves a multitude of cell types, chemical mediators and …

Subcellular localization and role of lipin-1 in human macrophages

M Valdearcos, E Esquinas, C Meana… - The Journal of …, 2011 - journals.aai.org
The lipins have been described as metabolic enzymes that regulate lipid biosynthesis and
also signaling processes by controlling the cellular concentration of bioactive lipids …

Monocyte-macrophages and T cells in atherosclerosis

I Tabas, AH Lichtman - Immunity, 2017 - cell.com
Atherosclerosis is an arterial disease process characterized by the focal subendothelial
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells …