Viral involvement in Alzheimer's disease

A Sait, C Angeli, AJ Doig, PJR Day - ACS chemical neuroscience, 2021‏ - ACS Publications
Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Using feature selection and Bayesian network identify cancer subtypes based on proteomic data

Y Wang, X Gao, X Ru, P Sun, J Wang - Journal of Proteomics, 2023‏ - Elsevier
Abstract The Cancer Proteome Atlas (TCPA) project collects reverse-phase protein arrays
(RPPA)-based proteome datasets from nearly 8000 samples across 32 cancer types. This …

ADAMTSL2 is a potential prognostic biomarker and immunotherapeutic target for colorectal cancer: Bioinformatic analysis and experimental verification

Z Huang, X Hu, Y Wei, Y Lai, J Qi, J Pang, K Huang… - Plos one, 2024‏ - journals.plos.org
The ADAMTS Like 2 (ADAMTSL2) mutation has been identified to be associated with
different human genetic diseases. The role of ADAMTSL2 is unclear in colorectal cancer …

PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients

Q Nie, H Cao, JW Yang, T Liu, B Wang - Scientific Reports, 2023‏ - nature.com
Abstract The PI3K/Akt signalling pathway is associated with the occurrence and
development of tumours and significantly affects the prognosis of patients. We established a …

Identification of STEAP3-based molecular subtype and risk model in ovarian cancer

Z Zhao, C Sun, J Hou, P Yu, Y Wei, R Bai… - Journal of Ovarian …, 2023‏ - Springer
Background Ovarian cancer (OC) is one of the most common malignancies in women. It has
a poor prognosis owing to its recurrence and metastasis. Unfortunately, reliable markers for …

Natural killer cell-related prognosis signature predicts immune response in colon cancer patients

M Li, J Song, L Wang, Q Wang, Q Huang… - Frontiers in …, 2023‏ - frontiersin.org
Background: Natural killer (NK) cells are crucial components of the innate immune system
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …

Acetylation model predicts prognosis of patients and affects immune microenvironment infiltration in epithelial ovarian carcinoma

X Wang, X Li, L Wei, Y Yu, Y Hazaisihan, L Tao… - Journal of Ovarian …, 2024‏ - Springer
Background Epithelial ovarian carcinoma (EOC) is a prevalent gynaecological malignancy.
The prognosis of patients with EOC is related to acetylation modifications and immune …

[HTML][HTML] Molecular characteristics, oncogenic roles, and relevant immune and pharmacogenomic features of NEK2 in gastric cancer

Z Wu, J Zheng, H Zhang, N Shen, X Luo, C Shen… - International …, 2023‏ - Elsevier
Gastric cancer (GC) is the most common form of gastrointestinal cancer, with a high mortality
rate and limited treatment options. High levels of NEK2 are associated with malignant …

Identification of a basement membrane-related gene signature for predicting prognosis and estimating the tumor immune microenvironment in breast cancer

J Cai, X Zhang, W **e, Z Li, W Liu, A Liu - Frontiers in Endocrinology, 2022‏ - frontiersin.org
Introduction Breast cancer (BC) is the most common malignancy in the world and has a high
cancer-related mortality rate. Basement membranes (BMs) guide cell polarity, differentiation …

[HTML][HTML] Effect of colorectal cancer stem cells on the development and metastasis of colorectal cancer

RZ Deng, X Zheng, ZL Lu, M Yuan… - World Journal of …, 2024‏ - pmc.ncbi.nlm.nih.gov
The relevant mechanism of tumor-associated macrophages (TAMs) in the treatment of
colorectal cancer patients with immune checkpoint inhibitors (ICIs) is discussed, and the …