The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva

A Amann, B de Lacy Costello, W Miekisch… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis is a young field of research with its roots in antiquity. Antoine Lavoisier
discovered carbon dioxide in exhaled breath during the period 1777–1783, Wilhelm (Vilém) …

Hybrid volatolomics and disease detection

YY Broza, P Mochalski, V Ruzsanyi… - Angewandte Chemie …, 2015 - Wiley Online Library
This Review presents a concise, but not exhaustive, didactic overview of some of the main
concepts and approaches related to “volatolomics”—an emerging frontier for fast, risk‐free …

Analysis of exhaled breath for disease detection

A Amann, W Miekisch, J Schubert… - Annual review of …, 2014 - annualreviews.org
Breath analysis is a young field of research with great clinical potential. As a result of this
interest, researchers have developed new analytical techniques that permit real-time …

Evolution of clinical and environmental health applications of exhaled breath research: Review of methods and instrumentation for gas-phase, condensate, and …

MAG Wallace, JD Pleil - Analytica Chimica Acta, 2018 - Elsevier
Human breath, along with urine and blood, has long been one of the three major biological
media for assessing human health and environmental exposure. In fact, the detection of …

Exhaled volatile organic compounds of infection: a systematic review

WM Ahmed, O Lawal, TM Nijsen… - ACS Infectious …, 2017 - ACS Publications
With heightened global concern of microbial drug resistance, advanced methods for early
and accurate diagnosis of infection are urgently needed. Analysis of exhaled breath volatile …

[HTML][HTML] Bridging targeted and untargeted mass spectrometry-based metabolomics via hybrid approaches

L Chen, F Zhong, J Zhu - Metabolites, 2020 - mdpi.com
This mini-review aims to discuss the development and applications of mass spectrometry
(MS)-based hybrid approaches in metabolomics. Several recently developed hybrid …

Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis

WD Smith, E Bardin, L Cameron… - FEMS microbiology …, 2017 - academic.oup.com
Pseudomonas aeruginosa opportunistically infects the airways of patients with cystic fibrosis
and causes significant morbidity and mortality. Initial infection can often be eradicated …

Breath analysis for detection of viral infection, the current position of the field

O Gould, N Ratcliffe, E Król… - Journal of Breath …, 2020 - iopscience.iop.org
The COVID-19 pandemic has highlighted the importance of rapid, cost effective, accurate,
and non-invasive testing for viral infections. Volatile compounds (VCs) have been suggested …

[HTML][HTML] Modern approaches for detection of volatile organic compounds in metabolic studies focusing on pathogenic bacteria: Current state of the art

K Żuchowska, W Filipiak - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Pathogenic microorganisms produce numerous metabolites, including volatile organic
compounds (VOCs). Monitoring these metabolites in biological matrices (eg, urine, blood, or …

[HTML][HTML] A review of analytical techniques and their application in disease diagnosis in breathomics and salivaomics research

DJ Beale, OAH Jones, AV Karpe, S Dayalan… - International journal of …, 2016 - mdpi.com
The application of metabolomics to biological samples has been a key focus in systems
biology research, which is aimed at the development of rapid diagnostic methods and the …