Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …

A nanobody (Nb) is a registered trademark of Ablynx, referring to the single antigen‐binding
domain of heavy chain‐only antibodies (HCAbs) that are circulating in Camelidae. Nbs are …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for
rapid and sensitive protein detection and quantification in simple and robust formats for …

The formation of silenced and condensed heterochromatin foci involves enrichment of
heterochromatin protein 1 (HP1). HP1 can bridge chromatin segments and form liquid …

Transcription factors (TFs) consist of a DNA-binding domain and an activation domain (AD)
that are frequently considered to be independent and exchangeable modules. However …

Sera of camelids contain both conventional heterotetrameric antibodies and unique
functional heavy (H)-chain antibodies (HCAbs). The H chain of these homodimeric …

Postnatal growth of mammalian oocytes is accompanied by a progressive gain of DNA
methylation, which is predominantly mediated by DNMT3A, a de novo DNA …

Physical embodiment is a required component for robots that are structurally coupled with
their real-world environments. However, most socially interactive robots do not need to …

The inheritance of parental histones across the replication fork is thought to mediate
epigenetic memory. Here, we reveal that fission yeast Mrc1 (CLASPIN in humans) binds H3 …

The unique class of heavy chain–only antibodies, present in Camelidae, can be shrunk to
just the variable region of the heavy chain to yield VHHs, also called nanobodies. About one …