Medulloblastoma

PA Northcott, GW Robinson, CP Kratz… - Nature reviews Disease …, 2019 - nature.com
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours
of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog …

Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours

MT Makale, CR McDonald… - Nature Reviews …, 2017 - nature.com
Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …

Neurocognitive outcomes and interventions in long-term survivors of childhood cancer

KR Krull, KK Hardy, LS Kahalley… - Journal of Clinical …, 2018 - ascopubs.org
Recent research has demonstrated that survivors of childhood cancer are at risk for a myriad
of late effects that affect physical and mental quality of life. We discuss the patterns and …

Radiation-induced brain injury: a review

D Greene-Schloesser, ME Robbins, AM Peiffer… - Frontiers in …, 2012 - frontiersin.org
Approximately 100,000 primary and metastatic brain tumor patients/year in the US survive
long enough (> 6 months) to experience radiation-induced brain injury. Prior to 1970, the …

[HTML][HTML] Diffusion tensor imaging of the brain

AL Alexander, JE Lee, M Lazar, AS Field - Neurotherapeutics, 2007 - Elsevier
Diffusion tensor imaging (DTI) is a promising method for characterizing microstructural
changes or differences with neuropathology and treatment. The diffusion tensor may be …

MYB function in normal and cancer cells

RG Ramsay, TJ Gonda - Nature Reviews Cancer, 2008 - nature.com
The transcription factor MYB has a key role as a regulator of stem and progenitor cells in the
bone marrow, colonic crypts and a neurogenic region of the adult brain. It is in these …

Processing speed, attention, and working memory after treatment for medulloblastoma: an international, prospective, and longitudinal study

SL Palmer, C Armstrong, A Onar-Thomas… - Journal of Clinical …, 2013 - ascopubs.org
Purpose The current study prospectively examined processing speed (PS), broad attention
(BA), and working memory (WM) ability of patients diagnosed with medulloblastoma over a 5 …

Neurocognitive consequences of a paediatric brain tumour and its treatment: A meta‐analysis

MA De Ruiter, R Van Mourik… - … Medicine & Child …, 2013 - Wiley Online Library
Aim This meta‐analysis provides a systematic review of studies into intellectual and
attentional functioning of paediatric brain tumour survivors (PBTS) as assessed by two …

Core neurocognitive functions in children treated for posterior fossa tumors.

DJ Mabbott, L Penkman, A Witol, D Strother… - …, 2008 - psycnet.apa.org
Identifying cognitive deficits associated with pediatric brain tumors and their treatment is
important in delineating the mechanisms of intellectual decline often associated with these …

White matter growth as a mechanism of cognitive development in children

DJ Mabbott, M Noseworthy, E Bouffet, S Laughlin… - Neuroimage, 2006 - Elsevier
We examined the functional role of white matter growth in cognitive development.
Specifically, we used hierarchical regression analyses to test the unique contributions of age …